Evidence map›Paper›PMID 23365653›Full record

ArticlePloS one2013

Phylogenetic and temporal dynamics of human immunodeficiency virus type 1 CRF01_AE in China.

Jingrong Ye, Ruolei Xin, Shuangqing Yu, Lishi Bai, Weishi Wang, Tingchen Wu, Xueli Su, Hongyan Lu, Xinghuo Pang, Hong Yan and 3 more

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jingrong YeBeijing Center for Disease Prevention and Control, Beijing, China.
Ruolei Xin
Shuangqing Yu
Lishi Bai
Weishi Wang
Tingchen Wu
Xueli Su
Hongyan Lu
Xinghuo Pang
Hong Yan
Xia Feng
Xiong He
Yi Zeng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the epidemic history of HIV-1 CRF01_AE in China, 408 fragments of gag gene sequences of CRF01_AE sampled in 2002-2010 were determined from different geographical regions and risk populations in China. Phylogenetic analysis indicates that the CRF01_AE sequences can be grouped into four clusters, suggesting that at least four genetically independent CRF01_AE descendants are circulating in China, of which two were closely related to the isolates from Thailand and Vietnam. Cluster 1 has the most extensive distribution in China. In North China, cluster 1 and cluster 4 were mainly transmitted through homosexuality.The real substance of the recent HIV-1 epidemic in men who have sex with men(MSM) of North China is a rapid spread of CRF01_AE, or rather two distinctive natives CRF01_AE.The time of the most recent common ancestor (tMRCA) of four CRF01_AE clusters ranged from the years 1990.9 to 2003.8 in different regions of China. This is the first phylogenetic and temporal dynamics study of HIV-1 CRF01_AE in China.

Indexed as

Multigene FamilyAdultAgedChinaFemalegag Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedPhylogenyRisk FactorsSexual BehaviorTime Factorsgag Gene Products, Human Immunodeficiency Virus

Identifiers

PMID23365653
PMCPMC3554705

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.