ReviewTheScientificWorldJournal2013
Goblet cell carcinoids of the appendix.
Review in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Extra-Appendiceal Neuroendocrine Expressing Goblet Cell Adenocarcinoma of the Cecum-A Case Report and Brief Review of the Literature.Reports (MDPI) · 2024Article
- Survival among 148 patients with an incidentally detected appendiceal tumours at surgery for acute appendicitis: a population-based cohort follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- The Optimal Approach to Surgical Management of Goblet Cell Carcinoid of the Appendix: A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Superiority ofCancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Case report: A rare case of coexistence of low-grade appendiceal mucinous neoplasia and goblet cell adenocarcinoma in the appendix.Frontiers in oncology · 2024Article
- The Vermiform Appendix and Its Pathologies.Cancers · 2023Review
- Appendiceal Goblet Cell Carcinoma: Role of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC).Indian journal of surgical oncology · 2023Review
- Goblet Cell Carcinoma of the Appendix with Synchronous Adenocarcinoma of the Cecum: Distinct or Related Entities?Diseases (Basel, Switzerland) · 2022Article
- Review
- Advanced appendiceal goblet cell carcinoids with intestinal obstruction: two case reports.Clinical journal of gastroenterology · 2020Article
- Somatostatin receptor scintigraphy in the follow up of neuroendocrine neoplasms of appendix.World journal of clinical cases · 2020Article
- ΔNp73 status in peritoneal and ovarian dissemination of appendicular adenocarcinoids (goblet cells).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019Article
- Endoscopic diagnosis of a goblet cell carcinoid tumour of the appendix.BMJ case reports · 2018Article
- Goblet cell carcinomas of the appendix: rare but aggressive neoplasms with challenging management.Endocrine connections · 2018Article
- Frequency, characteristics and outcomes of appendicular neuroendocrine tumors: A cross-sectional study from an academic tertiary care hospital.Annals of medicine and surgery (2012) · 2017Article
- Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.Journal of gastrointestinal oncology · 2017Article
- Goblet cell carcinoids of the appendix: Tumor biology, mutations and management strategies.World journal of gastrointestinal surgery · 2016Review
- Mixed Adeno-neuroendocrine Carcinoma: An Aggressive Clinical Entity.Annals of surgical oncology · 2016Article
- Pathology of Mucinous Appendiceal Tumors and Pseudomyxoma Peritonei.Indian journal of surgical oncology · 2016Review
- Epidemiology and classification of gastroenteropancreatic neuroendocrine neoplasms using current coding criteria.The British journal of surgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Goblet cell carcinoid (GCC) tumors are a rare subgroup of neuroendocrine tumors almost exclusively originating in the appendix. The tumor most often presents in the fifth or sixth decade with a clinical picture of appendicitis or in advanced cases an abdominal mass associated with abdominal pain. Histologically tumors are most often positive for chromogranin A and synaptophysin, however, less homogenous than for classic appendix carcinoids. The malignant potential is higher than that for the classic appendix carcinoids due to local spread and distant metastases at diagnosis and the proliferation markers (Ki67 index) may determine prognosis. Octreotide receptor scintigraphy is usually negative while CT/MRI scans may be useful. Chromogranin A is usually negative and other biomarkers related to the mucinous component or the tumor (CEA, CA-19-9, and CA-125) may be used. Surgery is the main treatment with appendectomy and right hemicolectomy while patients with disseminated disease should be treated with chemotherapy. Overall 5-year survival is approximately 75%. The diagnosis and treatment of GCC tumors should be restricted to high volume NET centers in order to accumulate knowledge and improve survival in GCC NET patients. The aim of this paper is to update on epidemiology, clinical presentation, and diagnostic markers including Ki67 index, treatment, and survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.