Evidence map›Paper›PMID 23365456›Full record

ReviewMolecular & cellular proteomics : MCP2013

Developments in the identification of glycan biomarkers for the detection of cancer.

L Renee Ruhaak, Suzanne Miyamoto, Carlito B Lebrilla

Abstract readReview
In one paragraph

Review in Molecular & cellular proteomics : MCP, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Glycan Fingerprint of Malignant Pleural Mesothelioma.International journal of molecular sciences · 2026
    Article
  2. Review
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  13. IntegratedCells · 2021
    Article
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  19. Article
  20. Cancer biologics made in plants.Current opinion in biotechnology · 2020
    Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L Renee RuhaakDepartment of Chemistry, University of California Davis, Davis, California 95616, USA.
Suzanne Miyamoto
Carlito B Lebrilla

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in glycosylation readily occur in cancer and other disease states. Thanks to recent advances in the development of analytical techniques and instrumentation, especially in mass spectrometry, it is now possible to identify blood-derived glycan-based biomarkers using glycomics strategies. This review is an overview of the developments made in the search for glycan-based cancer biomarkers and the technologies currently in use. It is anticipated that the progressing instrumental and bioinformatics developments will allow the identification of relevant glycan biomarkers for the diagnosis, early detection, and monitoring of cancer treatment with sufficient sensitivity and specificity for clinical use.

Indexed as

AnimalsAntigens, Tumor-Associated, CarbohydrateCarbohydrate ConformationCarbohydrate SequenceGlycoproteinsGlycosylationHumansMass SpectrometryMolecular Sequence DataNeoplasmsPolysaccharidesPrognosisProtein Processing, Post-TranslationalProteomeAntigens, Tumor-Associated, CarbohydrateGlycoproteinsPolysaccharidesProteome

Identifiers

PMID23365456
PMCPMC3617331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.