Evidence map›Paper›PMID 23365202›Full record

ArticleClinical and vaccine immunology : CVI2013

Serotype sensitivity of a lateral flow immunoassay for cryptococcal antigen.

Marcellene A Gates-Hollingsworth, Thomas R Kozel

Abstract readEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical Aspects of Immune Damage in Cryptococcosis.Current fungal infection reports · 2019
    Article
  9. Article
  10. Review
  11. Evolution of Cryptococcal Antigen Testing: What is new?Current fungal infection reports · 2016
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Update on fungal diagnostics.Current infectious disease reports · 2014
    Article
  18. Fungal diagnostics.Cold Spring Harbor perspectives in medicine · 2014
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marcellene A Gates-HollingsworthUniversity of Nevada School of Medicine, Reno, NV, USA.
Thomas R Kozel

Funding

Immunoassay for capsular antigen for rapid diagnosis of anthraxR01AI093365 · NIAID · UNIVERSITY OF NEVADA RENO · PI KOZEL, THOMAS R · 2011 to 2015
$3.4M
Cryptococcal polysaccharide-phagocytosis inhibitionR01AI014209 · NIAID · UNIVERSITY OF NEVADA RENO · PI KOZEL, THOMAS R · 1985 to 2009
$1.9M
CRYPTOCOCCAL POLYSACCHARIDE--PHAGOCYTOSIS INHIBITIONR37AI014209 · NIAID · UNIVERSITY OF NEVADA RENO · PI KOZEL, THOMAS R · 1995 to 2004
$1.5M
NIAID NIH HHS AI014209NIAID NIH HHS AI093365NIAID NIH HHS R01 AI014209NIAID NIH HHS R01 AI093365NIAID NIH HHS R37 AI014209
6 · The paper itself

Abstract

To meet the needs of a global community, an immunoassay for cryptococcal antigen (CrAg) must have high sensitivity for CrAg of all major serotypes. A new immunoassay for CrAg in lateral flow format was evaluated and found to have a high sensitivity for detection of serotypes A, B, C, and D.

Indexed as

Antigens, FungalClinical Laboratory TechniquesCryptococcosisCryptococcus neoformansHumansImmunoassaySensitivity and SpecificityAntigens, Fungal

Identifiers

PMID23365202
PMCPMC3623403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.