Trial reportTwin research and human genetics : the official journal of the International Society for Twin Studies2012
The Minnesota Center for Twin and Family Research genome-wide association study.
Trial report in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity.Human reproduction (Oxford, England) · 2024Pooled it
- Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis.Molecular psychiatry · 2022Pooled it
- Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes.PLoS genetics · 2018Pooled it
- Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.Behavior genetics · 2016Pooled it
- GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.Science (New York, N.Y.) · 2013Pooled it
- An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design.PLoS genetics · 2011Pooled it
- Determination of Zygosity in Adult Chinese Twins Using the 450K Methylation Array versus Questionnaire Data.PloS one · 2015Trial
- Behavioral Disinhibition Model of Addiction: A Review and New Findings from the Minnesota Twin Family Study.Behavior genetics · 2026Review
- A genetic common factor underlying self-reported math ability and highest math class taken.Molecular psychiatry · 2025Article
- Association of Recreational Cannabis Legalization with Frequency of Using Cannabis for Sleep.Journal of psychoactive drugs · 2025Article
- Evaluating substance use outcomes of recreational cannabis legalization using a unique co-twin control design.The American journal of drug and alcohol abuse · 2023Article
- Exploring Relationships Between Internalizing Problems and Risky Sexual Behavior: A Twin Study.Behavior genetics · 2023Article
- Simultaneous selection of multiple important single nucleotide polymorphisms in familial genome wide association studies data.Scientific reports · 2023Article
- Associations between polygenic risk of substance use and use disorder and alcohol, cannabis, and nicotine use in adolescence and young adulthood in a longitudinal twin study.Psychological medicine · 2023Article
- An Efficient Bayesian Method for Estimating the Degree of the Skewness of X Chromosome Inactivation Based on the Mixture of General Pedigrees and Unrelated Females.Biomolecules · 2023Article
- Longitudinal effects and environmental moderation ofDevelopment and psychopathology · 2022Article
- Adolescent cannabis use and adult psychoticism: A longitudinal co-twin control analysis using data from two cohorts.Journal of abnormal psychology · 2021Article
- The role of parental genotype in predicting offspring years of education: evidence for genetic nurture.Molecular psychiatry · 2021Article
- A statistical measure for the skewness of X chromosome inactivation for quantitative traits and its application to the MCTFR data.BMC genomic data · 2021Article
- Genome-Wide SNP Analysis for Milk Performance Traits in Indigenous Sheep: A Case Study in the Egyptian Barki Sheep.Animals : an open access journal from MDPI · 2021Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
As part of the Genes, Environment and Development Initiative, the Minnesota Center for Twin and Family Research (MCTFR) undertook a genome-wide association study, which we describe here. A total of 8,405 research participants, clustered in four-member families, have been successfully genotyped on 527,829 single nucleotide polymorphism (SNP) markers using lllumina's Human660W-Ouad array. Quality control screening of samples and markers as well as SNP imputation procedures are described. We also describe methods for ancestry control and how the familial clustering of the MCTFR sample can be accounted for in the analysis using a Rapid Feasible Generalized Least Squares algorithm. The rich longitudinal MCTFR assessments provide numerous opportunities for collaboration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.