Evidence map›Paper›PMID 23363307›Full record

ArticleJournal of alternative and complementary medicine (New York, N.Y.)2013

Acupuncture and in vitro fertilization: a retrospective chart review.

Lee E Hullender Rubin, Michael S Opsahl, Lisa Taylor-Swanson, Deborah L Ackerman

Open access · greenAbstract read
In one paragraph

Article in Journal of alternative and complementary medicine (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. GV 20's Role inMedical acupuncture · 2019
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lee E Hullender RubinOregon College of Oriental Medicine, Portland, OR 97209, USA. lrubin@ocom.edu
Michael S Opsahl
Lisa Taylor-Swanson
Deborah L Ackerman
Oregon College of Oriental Medicine · USReproductive Science Center · USUniversity of Washington · US

Funding

Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
Acupuncture Practitioner Research Education EnhancementR25AT002879 · NCCIH · OREGON COLLEGE OF ORIENTAL MEDICINE · PI ACKERMAN, DEBORAH · 2005 to 2011
$804k
NCCIH NIH HHS R2S AT002879
6 · The paper itself

Abstract

objectivesIn 2007, Craig et al. reported the results of a randomized controlled trial in which a standardized acupuncture protocol performed on the day of embryo transfer (ET) resulted in lower pregnancy rates after in vitro fertilization (IVF). Between 2005 and 2007, the Craig protocol was used by one of the authors (LHR) at an infertility clinic unaffiliated with the Craig et al. trial. The objective was to retrospectively review clinic records to evaluate the effect of the Craig protocol in both donor and nondonor IVF cycles on four outcomes: (1) live births; (2) biochemical pregnancies; (3) adverse outcomes; and (4) live births in nondonor cycles across age groups established by the Society for Assisted Reproductive Technology.

designThe study design was a retrospective chart review.

settingThe study was conducted at a private infertility clinic. PATIENT(S): Patients underwent fresh, donor (N=70) or nondonor (N=402) IVF-ET. INTERVENTION(S): The Craig protocol included the following points before ET: GV-20, CV-6, ST-29, SP-8, PC-6, LV-3; Shenmen and Brain on the left ear; and Uterus and Endocrine on the right ear. After transfer the points were LI-4, SP-10, ST-36, SP-6, KI-3; Uterus and Endocrine on the left ear; and Shenmen and Brain on the right ear. MAIN OUTCOME MEASURE(S): Live births (LB) beyond 24 weeks' gestation was the main outcome measure. RESULT(S): In nondonor IVF cycles, there were no differences in LB across age groups (odds ratio [OR]=1.04, 95% confidence interval [CI] 0.68-1.57), biochemical pregnancies (OR=0.60, 95% CI 0.27-1.33), or adverse outcomes (OR=0.63, 95% CI 0.31-1.26). In donor cycles, LB were higher in the acupuncture group (relative risk=1.31, 95% CI 1.02-1.71).

conclusionsIn this observational study, the Craig protocol was not found to lower IVF LB. In fact, the Craig protocol was associated with higher LB in donor cycles. These findings should be considered cautiously because more adequately powered, randomized research is needed.

Indexed as

Acupuncture TherapyFertilization in VitroAdultEmbryo TransferFemaleHumansInfant, NewbornInfertilityMalePregnancyRetrospective Studies

Identifiers

PMID23363307
PMCPMC3700457
OpenAlexW2075344899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.