ArticlePlanta2013
Multiple ketolases involved in light regulation of canthaxanthin biosynthesis in Nostoc punctiforme PCC 73102.
Article in Planta, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Genetic and biochemical diversity of terpene biosynthesis in cyanobacterial strains from tropical soda lakes.Frontiers in microbiology · 2025Article
- Production of Carotenoids and Phospholipids byMarine drugs · 2022Article
- Diversity and Evolution of Carotenoid Biosynthesis from Prokaryotes to Plants.Advances in experimental medicine and biology · 2021Review
- Synthesis, Regulation and Degradation of Carotenoids Under Low Level UV-B Radiation in the Filamentous CyanobacteriumFrontiers in microbiology · 2020Article
- Antioxidant Protection from UV- and Light-Stress Related to Carotenoid Structures.Antioxidants (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the genome of Nostoc punctiforme PCC 73102, three functional β-carotene ketolase genes exist, one of the crtO and two of the crtW type. They were all expressed and their corresponding enzymes were functional inserting 4-keto groups into β-carotene as shown by functional pathway complementation in Escherichia coli. They all synthesized canthaxanthin but with different efficiencies. Canthaxanthin is the photoprotective carotenoid of N. punctiforme PCC 73102. Under high-light stress, its synthesis was enhanced. This was caused by up-regulation of the transcripts of two genes in combination. The first crtB-encoding phytoene synthase is the gate way enzyme of carotenogenesis resulting in an increased inflow into the pathway. The second was the ketolase gene crtW148 which in high light takes over β-carotene conversion into canthaxanthin from the other ketolases. The other ketolases were down-regulated under high-light conditions. CrtW148 was also exclusively responsible for the last step in 4-keto-myxoxanthophyll synthesis.
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Registered trials
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