ArticleMolecular diversity2013
A novel enzyme-catalyzed synthesis of N-substituted pyrrole derivatives.
Article in Molecular diversity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0 citing papers in PubMed, 17 citations in OpenAlex.
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5 authors at 1 institution in 1 country.
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Abstract
A novel method for the synthesis of substituted pyrroles catalyzed by α-amylase from hog pancreas via Paal-Knorr reaction was developed. A series of pyrrole derivatives were synthesized under mild conditions and the products were obtained with good to excellent yields (60-99 %). The impact of factors, such as solvents, enzyme amount, and temperature, on the reaction were investigated. This study reports an efficient route for the synthesis of N-substituted pyrrole derivatives.
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