ReviewCurrent opinion in pulmonary medicine2013
Sex and race factors in early-onset COPD.
Review in Current opinion in pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Social determinants of health in clinical trials examining long-term oral antibiotics in COPD: a systematic review.ERJ open research · 2026Review
- Association of GLP1RAs with risk of chronic obstructive pulmonary disease: evidence from drug target Mendelian randomization.Diabetology & metabolic syndrome · 2025Article
- Prevalence and clinical correlates of chronic obstructive pulmonary disease in heart failure patients: a cross-sectional study in China.Frontiers in medicine · 2025Article
- Progesterone (P4) ameliorates cigarette smoke-induced chronic obstructive pulmonary disease (COPD).Molecular medicine (Cambridge, Mass.) · 2024Article
- The relationship of fat and muscle measurements with emphysema and bronchial wall thickening in smokers.ERJ open research · 2024Article
- Prevalence, risk factors, and mortality of COPD in young people in the USA: results from a population-based retrospective cohort.BMJ open respiratory research · 2023Article
- Community-Based Approach to Assess Obstructive Respiratory Diseases and Risk in Urban African American Churches.Journal of immigrant and minority health · 2023Article
- Patient-specific risk factors contributing to blood culture contamination.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
- Article
- Poor Cognitive Function Is Associated with Obstructive Lung Diseases in Taiwanese Adults.International journal of environmental research and public health · 2021Article
- Sex-Steroid Signaling in Lung Diseases and Inflammation.Advances in experimental medicine and biology · 2021Article
- Chronic hypoxaemia and gender status modulate adiponectin plasmatic level and its multimer proportion in severe COPD patients: new endotypic presentation?BMC pulmonary medicine · 2020Article
- Never-smoker African-American women suffer more from COPD compared with never-smoker Caucasian women.European respiratory review : an official journal of the European Respiratory Society · 2020Article
- Asthma, Chronic Obstructive Pulmonary Disease, and Subsequent Risk for Incident Rheumatoid Arthritis Among Women: A Prospective Cohort Study.Arthritis & rheumatology (Hoboken, N.J.) · 2020Article
- Association Between E-Cigarette Use and Chronic Obstructive Pulmonary Disease by Smoking Status: Behavioral Risk Factor Surveillance System 2016 and 2017.American journal of preventive medicine · 2020Article
- Association of use of cleaning products with respiratory health in a Canadian birth cohort.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Article
- A Between Ethnicities Comparison of Chronic Obstructive Pulmonary Disease Genetic Risk.Frontiers in genetics · 2020Article
- Race, Ethnicity, Socioeconomic Status, and Chronic Lung Disease in the U.S.Research in health science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purpose of reviewUnlike other major diseases, mortality for chronic obstructive pulmonary disease (COPD) continues to increase. In recent years, COPD has evolved to increasingly affect women, minorities, and individuals from low socioeconomic groups. In women and African-Americans, evidence exists supporting the earlier development of COPD after less lifetime smoking. This review highlights new information on racial and sex differences in COPD. RECENT
findingsSex and related hormonal changes affect T-cell phenotypes, immunity, and smoking-related metabolism of toxic intermediate metabolites. Alterations in the bronchoalveolar lavage proteome of women, but not of men, have allowed the differentiation of healthy female smokers from smokers with COPD. Sex significantly influences levels of inflammatory cytokines and correlates with different clinical and physiological parameters in female COPD patients. African-Americans with COPD are younger, smoke less, are more likely to currently smoke, and have worse health-related quality of life (QOL). African-Americans are more likely to report hospitalized exacerbations that impact QOL. African-Americans with COPD and asthma are nearly four times more likely to experience exacerbations. SUMMARY: There are sex-specific and race-related differences in the manifestation of COPD. These differences warrant further physiologic, biologic, and genetic investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.