Evidence map›Paper›PMID 23361135›Full record

ArticlePhysical biology2013

Prediction of heart rate response to conclusion of the spontaneous breathing trial by fluctuation dissipation theory.

Man Chen, Liang Ren Niestemski, Robert Prevost, Michael McRae, Sharath Cholleti, Gabriel Najarro, Timothy G Buchman, Michael W Deem

Open access · greenAbstract read
In one paragraph

Article in Physical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Man ChenPhysics & Astronomy Department, Rice University, Houston, TX, USA.
Liang Ren Niestemski
Robert Prevost
Michael McRae
Sharath Cholleti
Gabriel Najarro
Timothy G Buchman
Michael W Deem
Rice University · USEmory University · US

Funding

Predicting Patient Subpopulation Dynamics from Fluctuation TheoryR01GM100468 · NIGMS · RICE UNIVERSITY · PI DEEM, MICHAEL W · 2011 to 2014
$1.5M
NIGMS NIH HHS R01 GM100468
6 · The paper itself

Abstract

The non-equilibrium fluctuation dissipation theorem is applied to predict how critically ill patients respond to treatment, based upon data currently collected by standard hospital monitoring devices. This framework is demonstrated on a common procedure in critical care: the spontaneous breathing trial. It is shown that the responses of groups of similar patients to the spontaneous breathing trial can be predicted by the non-equilibrium fluctuation dissipation approach. This mathematical framework, when fully formed and applied to other clinical interventions, may serve as part of the basis for personalized critical care.

Indexed as

Heart RateModels, BiologicalRespiratory Function TestsComputer SimulationCritical CareCritical IllnessHumansRespiration

Identifiers

PMID23361135
PMCPMC3635490
OpenAlexW2084922745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.