ArticleCarbohydrate research2013
The capsular polysaccharide and lipopolysaccharide structures of two carbapenem resistant Klebsiella pneumoniae outbreak isolates.
Article in Carbohydrate research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Differential virulence potential of different clades of multidrug-resistantMicrobiology spectrum · 2026Article
- Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes.PLoS biology · 2026Article
- Differential virulence potential of different clades of multidrug-resistantmedRxiv : the preprint server for health sciences · 2026Article
- A multivalent capsule vaccine protects against Klebsiella pneumoniae bloodstream infections in healthy and immunocompromised mice.NPJ vaccines · 2025Article
- Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase frommBio · 2025Article
- Tackling salmonellosis: A comprehensive exploration of risks factors, impacts, and solutions.Open veterinary journal · 2024Review
- Thiol-Mediated Uptake of a Cysteine-Containing Nanobody for Anticancer Drug Delivery.ACS central science · 2023Article
- Development of a Bispecific Antibody Targeting Clinical Isolates of Acinetobacter baumannii.The Journal of infectious diseases · 2023Article
- Review
- Monoclonal Antibody Therapy againstInfection and immunity · 2021Article
- Serum Antibody Responses against Carbapenem-Resistant Klebsiella pneumoniae in Infected Patients.mSphere · 2021Article
- Identification of a newly isolated lytic bacteriophage against K24 capsular type, carbapenem resistant Klebsiella pneumoniae isolates.Scientific reports · 2020Article
- Article
- Identification of Two Depolymerases From Phage IME205 and Their Antivirulent Functions on K47 Capsule ofFrontiers in microbiology · 2020Article
- Microbe-focused glycan array screening platform.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Targeting the Sugary Armor ofFrontiers in cellular and infection microbiology · 2019Review
- Influence of Bacterial Biofilm Polysaccharide Structure on Interactions with Antimicrobial Peptides: A Study onInternational journal of molecular sciences · 2018Article
- Genome analysis of clinical multilocus sequence Type 11 Klebsiella pneumoniae from China.Microbial genomics · 2018Article
- A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae.Angewandte Chemie (International ed. in English) · 2017Article
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Authors and funding
9 authors.
Funding
Abstract
Carbapenem resistant Klebsiella pneumoniae (CRKP) are isolated with increasing frequency, especially from immunocompromized patients. The capsular polysaccharide (CPS) types of CPKP were not determined. Investigation of two CRKP isolates from a 2011 outbreak at the Clinical Center, the National Institutes of Health, identified a new capsular type shared by the two isolates, similar to K. pneumonia K19 and K34 but structurally different than any published K. pneumoniae CPS repeating unit: The LPS of the two isolates was found to have no O-specific polysaccharide and the chemical structure of the core oligosaccharides agreed with the published data. If this structure type will be prevalent among CPKP isolates, our findings could facilitate rapid diagnosis and help to develop new therapeutic solutions to this antibiotic resistant pathogen.
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