ArticleJournal of the American Chemical Society2013
Dynamic DNA assemblies mediated by binding-induced DNA strand displacement.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Kinetics and Activation Strategies in Toehold-Mediated and Toehold-Free DNA Strand Displacement.Biosensors · 2025Review
- Development of a mix-and-read assay for human asprosin using antibody-oligonucleotide probes and thermofluorimetric analysis.Analytical methods : advancing methods and applications · 2024Article
- One-tube B7-H3 detection based on isothermal exponential amplification and dendritic hybridization chain reaction.Nanoscale advances · 2024Article
- Programming conformational cooperativity to regulate allosteric protein-oligonucleotide signal transduction.Nature communications · 2023Article
- Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer.Nucleic acids research · 2023Article
- DNA Strand Displacement Driven by Host-Guest Interactions.Journal of the American Chemical Society · 2022Article
- Chemiluminescent screening of specific hybridoma cells via a proximity-rolling circle activated enzymatic switch.Communications biology · 2022Article
- Controlling Dynamic DNA Reactions at the Surface of Single-Walled Carbon Nanotube Electrodes to Design Hybridization Platforms with a Specific Amperometric Readout.Analytical chemistry · 2022Article
- Intelligent demethylase-driven DNAzyme sensor for highly reliable metal-ion imaging in living cells.Chemical science · 2021Article
- Dynamically elongated associative toehold for tuning DNA circuit kinetics and thermodynamics.Nucleic acids research · 2021Article
- Amplified detection of nucleic acids and proteins using an isothermal proximity CRISPR Cas12a assay.Chemical science · 2021Article
- A fluorescent immunosensor for determination and imaging of circulating tumor cells based on a bifunctional DNA nanomachine.Mikrochimica acta · 2020Article
- Article
- Designed and Evolved Nucleic Acid Nanotechnology: Contrast and Complementarity.Bioconjugate chemistry · 2019Review
- DNAzyme Catalyzed Tyramide Depositing Reaction forTheranostics · 2019Article
- An ultrasensitive flow cytometric immunoassay based on bead surface-initiated template-free DNA extension.Chemical science · 2018Article
- Proximity hybridization triggered strand displacement and DNAzyme assisted strand recycling for ATP fluorescence detectionRSC advances · 2018Article
- A DNA-Based Assay for Digoxin Detection.Biosensors · 2018Article
- DNA Self-assembly Catalyzed by Artificial Agents.Scientific reports · 2017Article
- Antibody-powered nucleic acid release using a DNA-based nanomachine.Nature communications · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Dynamic DNA assemblies, including catalytic DNA circuits, DNA nanomachines, molecular translators, and reconfigurable nanostructures, have shown promising potential to regulate cell functions, deliver therapeutic reagents, and amplify detection signals for molecular diagnostics and imaging. However, such applications of dynamic DNA assembly systems have been limited to nucleic acids and a few small molecules, due to the limited approaches to trigger the DNA assemblies. Herein, we describe a binding-induced DNA strand displacement strategy that can convert protein binding to the release of a predesigned output DNA at room temperature with high conversion efficiency and low background. This strategy allows us to construct dynamic DNA assembly systems that are able to respond to specific protein binding, opening an opportunity to initiate dynamic DNA assembly by proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.