ArticleThe American journal of tropical medicine and hygiene2013
Isolation and molecular characterization of Leptospira interrogans and Leptospira borgpetersenii isolates from the urban rat populations of Kuala Lumpur, Malaysia.
Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Emerging zoonotic diseases in Southeast Asia in the period 2011-2022: a systematic literature review.The veterinary quarterly · 2024Pooled it
- Retrospective Molecular Detection and Characterization of PathogenicTropical medicine and infectious disease · 2026Article
- Leptospirosis in humans and animals in Malaysia: A review from 1976 to 2023.Veterinary world · 2025Review
- Review
- Seroprevalence of pathogenicFrontiers in veterinary science · 2024Review
- Leptospirosis in Malaysia: current status, insights, and future prospects.Journal of physiological anthropology · 2023Review
- A Multi-landscape Assessment of Leptospira Prevalence on a Diversity of Small Mammals.EcoHealth · 2023Article
- Identification of PathogenicPathogens (Basel, Switzerland) · 2023Article
- Application of Multilocus Sequence Typing for the Characterization ofTropical medicine and infectious disease · 2023Article
- Prevalence of PathogenicPathogens (Basel, Switzerland) · 2022Article
- Rats and the city: Implications of urbanization on zoonotic disease risk in Southeast Asia.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Epidemiology of Leptospirosis: The First Literature Review of the Neglected Disease in the Middle East.Tropical medicine and infectious disease · 2022Review
- Serological and molecular characteristics of pathogenic Leptospira in rodent populations in Fujian Province, China, 2018-2020.BMC microbiology · 2022Article
- Epidemiological determinants of leptospirosis in rural and urban districts of Maharashtra, India.Journal of family medicine and primary care · 2021Article
- Detection and characterization ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Room-temperature stable loop-mediated isothermal amplification (LAMP) reagents to detect leptospiral DNA.Asian biomedicine : research, reviews and news · 2021Article
- Detection of Leptospira kmetyi at recreational areas in Peninsular Malaysia.Environmental monitoring and assessment · 2020Article
- First report of pathogenic Leptospira spp. isolated from urine and kidneys of naturally infected cats.PloS one · 2020Article
- Seroprevalence of Anti-The American journal of tropical medicine and hygiene · 2019Article
- Leptospira infection in rats: A literature review of global prevalence and distribution.PLoS neglected tropical diseases · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rats are considered the principal maintenance hosts of Leptospira. The objectives of this study were isolation and identification of Leptospira serovars circulating among urban rat populations in Kuala Lumpur. Three hundred urban rats (73% Rattus rattus and 27% R. norvegicus) from three different sites were trapped. Twenty cultures were positive for Leptospira using dark-field microscopy. R. rattus was the dominant carrier (70%). Polymerase chain reaction (PCR) confirmed that all isolates were pathogenic Leptospira species. Two Leptospira serogroups, Javanica and Bataviae, were identified using microscopic agglutination test (MAT). Pulsed-field gel electrophoresis (PFGE) identified two serovars in the urban rat populations: L. borgpetersenii serovar Javanica (85%) and L. interrogans serovar Bataviae (15%). We conclude that these two serovars are the major serovars circulating among the urban rat populations in Kuala Lumpur. Despite the low infection rate reported, the high pathogenicity of these serovars raises concern of public health risks caused by rodent transmission of leptospirosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.