Evidence map›Paper›PMID 23358424›Full record

ReviewNature reviews. Nephrology2013

Noninsulin glucose-lowering agents for the treatment of patients on dialysis.

Colleen Flynn, George L Bakris

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Clinical Significance of Serum lncRNA Cancer Susceptibility Candidate 2 (CASC2) for Chronic Renal Failure in Patients with Type 2 Diabetes.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  9. Review
  10. Article
  11. Prescribing for patients on dialysis.Australian prescriber · 2016
    Review
  12. Review
  13. The clinical application of linagliptin in Asians.Therapeutics and clinical risk management · 2015
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Colleen FlynnAmerican Society of Hypertension Comprehensive Hypertension Center, Section of Endocrinology, Diabetes and Metabolism, The University of Chicago Medicine, Chicago, IL 60637, USA.
George L Bakris
University of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a common complication of diabetes mellitus and the most common cause of end-stage renal disease (ESRD). As the worldwide prevalence of diabetes continues to increase, the number of patients with CKD will also increase. Therefore, it is essential that physicians know how to safely and effectively manage diabetes in the setting of CKD. Adequate glycaemic control in patients with diabetes is important to prevent ESRD and other complications and to decrease mortality. However, many glucose-lowering agents need to be dose-adjusted or should not be used in the setting of stage 3 CKD or higher (defined as an estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m(2)), particularly in patients with stage 5 CKD (eGFR <15 ml/min/1.73 m(2)) and in those receiving dialysis. Insulin therapy is appropriate for patients undergoing dialysis; however, several orally administered glucose-lowering agents can also be used safely in these patients. In this Review, we provide an overview of the use of noninsulin glucose-lowering agents in the dialysis population.

Indexed as

AdamantaneBiguanidesDiabetic NephropathiesDipeptidesDipeptidyl-Peptidase IV InhibitorsDisease ProgressionGlucagon-Like PeptidesGlycoside Hydrolase InhibitorsHumansHypoglycemic AgentsLinagliptinMeglumineMetforminNitrilesPiperidinesPurinesAdamantanealogliptinBiguanidesDipeptidesDipeptidyl-Peptidase IV InhibitorsGlucagon-Like PeptidesGlycoside Hydrolase InhibitorsHypoglycemic AgentsLinagliptinMeglumineMetforminNitrilesPiperidinesPurinesPyrazinesPyrrolidinesQuinazolinessaxagliptinSitagliptin PhosphateSulfonylurea CompoundsThiazolidinedionesTriazolesUracilVildagliptin

Identifiers

PMID23358424
OpenAlexW2036592965

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.