Evidence map›Paper›PMID 23357771›Full record

ArticleAntimicrobial agents and chemotherapy2013

Staphylococcus aureus biofilms promote horizontal transfer of antibiotic resistance.

Victoria J Savage, Ian Chopra, Alex J O'Neill

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed.

  1. Article
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  9. Observational
  10. A Novel Method to Monitor the Evolution of Antimicrobial Resistance inInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
  15. Isolation and characterization of multidrug-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Victoria J SavageAntimicrobial Research Centre and School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Ian Chopra
Alex J O'Neill

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth as a biofilm facilitates the emergence of antibiotic resistance by mutation in Staphylococcus aureus. Here we demonstrate that biofilm growth of this species also dramatically increases horizontal transfer of plasmid-borne antibiotic resistance determinants by conjugation/mobilization and that standard laboratory practices to induce conjugation in staphylococci achieve optimal efficiency owing to the presence of a biofilm.

Indexed as

Anti-Bacterial AgentsBiofilmsGene Transfer, HorizontalMicrobial Sensitivity TestsPlasmidsStaphylococcus aureusAnti-Bacterial Agents

Identifiers

PMID23357771
PMCPMC3623343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.