Evidence map›Paper›PMID 23357001›Full record

ArticleBiosensors & bioelectronics2013

Optical ATP biosensor for extracellular ATP measurement.

C Wang, C-Y C Huang, W-C Lin

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 40 citations in OpenAlex.

  1. Gold nanoparticle-based colorimetric detection of ATP via a label-free aptamer.Frontiers in bioengineering and biotechnology · 2026
    Article
  2. Review
  3. Review of Nitrification Monitoring and Control Strategies in Drinking Water System.International journal of environmental research and public health · 2022
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Imaging Adenosine Triphosphate (ATP).The Biological bulletin · 2016
    Review
  11. Review
  12. Energy metabolism of intervertebral disc under mechanical loading.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

C WangDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL 33146, USA.
C-Y C Huang
W-C Lin
University of Miami · USFlorida International University · US

Funding

Effects of mechanical loading on energy production of intervertebral disc cellsR03AR056101 · NIAMS · UNIVERSITY OF MIAMI CORAL GABLES · PI HUANG, CHUN-YUH · 2009 to 2011
$221k
NIAMS NIH HHS AR056101NIAMS NIH HHS R03 AR056101
6 · The paper itself

Abstract

Extracellular Adenosine-5'-triphosphate (ATP) is an important multi-functional molecule which can mediate numerous physiological activities by activating purinergic P2 receptors. The objective of this study was to develop a novel optical ATP sensor for in-situ extracellular ATP measurement in biological tissues. The optical ATP sensor was made by applying two layers of sol-gel coating to the end of an optical fiber probe end. The first layer contained ruthenium complex for sensing changes in oxygen concentration which resulted from oxidation of ATP by glycerol kinase and glycerol 3-phosphate oxidase entrapped in the second layer. It was demonstrated that the optical ATP sensor was capable of detecting ATP concentration at a broad range of 10(-3)mM to 1.5mM.A compensation method was established to enable the optical sensor to determine ATP concentration at different oxygen levels. This study also demonstrated the capability of ATP sensor to measure extracellular ATP content in biological tissues (i.e., porcine intervertebral disc). In addition, it was shown that the optical ATP sensor was not affected by pH and derivatives of extracellular ATP. Therefore, the newly developed optical ATP sensor is a good option for in-situ extracellular ATP measurement.

Indexed as

Optical DevicesAdenosine TriphosphateBiosensing TechniquesEquipment DesignEquipment Failure AnalysisExtracellular FluidFiber Optic TechnologyOxygenRefractometryAdenosine TriphosphateOxygen

Identifiers

PMID23357001
PMCPMC3593988
OpenAlexW2033233397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.