Evidence map›Paper›PMID 23356906›Full record

ArticleThe journal of physical chemistry. B2013

Sorting short fragments of single-stranded DNA with an evolving electric double layer.

Jiamin Wu, Shuang-Liang Zhao, Lizeng Gao, Jianzhong Wu, Di Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry. B, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiamin WuDepartment of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States.
Shuang-Liang Zhao
Lizeng Gao
Jianzhong Wu
Di Gao

Funding

10-Theory and Experiment for Genome Packaging in HBV NucleocapsidsR21AI077532 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI HJELM, REX PAUL, HU, JIANMING · 2009 to 2010
$474k
DNA Sequencing at a StretchR21HG004769 · NHGRI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAO, DI · 2008 to 2009
$369k
NHGRI NIH HHS R21 HG004769NIAID NIH HHS R21 AI077532NIAID NIH HHS R21-AI077532
6 · The paper itself

Abstract

We demonstrate a new procedure for separation of single-stranded DNA (ssDNA) fragments that are anchored to the surface of a gold electrode by end hybridization. The new separation procedure takes advantage of the strong yet evolving nonuniform electric field near the gold surface in contact with a buffer solution gradually being diluted with deionized water. Separation of short ssDNA fragments is demonstrated by monitoring the DNA at the gold surface with in situ fluorescence measurement. The experimental results can be rationalized with a simple theoretical model of electric double layer that relates the strength of the surface pulling force to the ionic concentration of the changing buffer solution.

Indexed as

DNA ProbesDNA, Single-StrandedElectricityElectrochemical TechniquesElectrodesGoldImmobilized Nucleic AcidsNucleic Acid HybridizationSpectrometry, FluorescenceWaterDNA ProbesDNA, Single-StrandedGoldImmobilized Nucleic AcidsWater

Identifiers

PMID23356906
PMCPMC3624732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.