Evidence map›Paper›PMID 23356729›Full record

ArticleExperimental and clinical psychopharmacology2013

Early and prolonged exposure to reward delay: effects on impulsive choice and alcohol self-administration in male rats.

Jeffrey S Stein, Patrick S Johnson, C Renee Renda, Rochelle R Smits, Kennan J Liston, Timothy A Shahan, Gregory J Madden

Abstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Selective chemogenetic inactivation of corticoaccumbal projections disrupts trait choice impulsivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
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  13. Article
  14. Reducing impulsive choice: VI. Delay-exposure training reduces aversion to delay-signaling stimuli.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Article
  15. Article
  16. Cognitive and behavioral training interventions to promote self-control.Journal of experimental psychology. Animal learning and cognition · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey S SteinDepartment of Psychology, Utah State University, 2810 Old Main Hill, Logan, UT 84322, USA. jeff.stein@aggiemail.usu.edu
Patrick S Johnson
C Renee Renda
Rochelle R Smits
Kennan J Liston
Timothy A Shahan
Gregory J Madden

Funding

Experimental Manipulations of Impulsivity: Effects on Gambling and Drug TakingR01DA029608 · NIDA · UTAH STATE UNIVERSITY · PI MADDEN, GREGORY J · 2010 to 2013
$957k
NIDA NIH HHS 1R01DA029605NIDA NIH HHS R01 DA029608
6 · The paper itself

Abstract

Naturally occurring impulsive choice has been found to positively predict alcohol consumption in rats. However, the extent to which experimental manipulation of impulsive choice may modify alcohol consumption remains unclear. In the present study, we sought to: (a) train low levels of impulsive choice in rats using early, prolonged exposure to reward delay, and (b) determine the effects of this manipulation on subsequent alcohol consumption. During a prolonged training regimen, three groups of male, adolescent Long-Evans rats (21-22 days old at intake) responded on a single lever for food rewards delivered after either a progressively increasing delay, a fixed delay, or no delay. Posttests of impulsive choice were conducted, as was an evaluation of alcohol consumption using a limited-access, two-bottle test. Following delay-exposure training, both groups of delay-exposed rats made significantly fewer impulsive choices than did rats in the no-delay group. In addition, fixed-delay rats consumed significantly more alcohol during daily, 30-min sessions than no-delay rats. Possible mechanisms of these effects are discussed, as is the significance of these findings to nonhuman models of addiction.

Indexed as

Choice BehaviorSelf AdministrationAnimalsEthanolMaleRatsEthanol

Identifiers

PMID23356729
PMCPMC3686290

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.