Observational studyCritical care (London, England)2013
The effect of acute kidney injury on long-term health-related quality of life: a prospective follow-up study.
Observational study in Critical care (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Japanese clinical practice guideline for acute kidney injury 2016.Clinical and experimental nephrology · 2018Guideline
- Health-related quality-of-life among survivors of acute kidney injury in the intensive care unit: a systematic review.Intensive care medicine · 2016Pooled it
- Discharge frailty following lung transplantation.Clinical transplantation · 2019Trial
- Article
- Holistic Patient-Centered Outcomes in Post-Acute Kidney Injury Care: Physical, Emotional, Cognitive, and Social Outcomes.Advances in kidney disease and health · 2025Review
- Tumour lysis syndrome.Nature reviews. Disease primers · 2024Review
- Associations of systolic blood pressure and in-hospital mortality in critically ill patients with acute kidney injury.International urology and nephrology · 2023Article
- Monocyte-to-lymphocyte ratio: a potential novel predictor for acute kidney injury in the intensive care unit.Renal failure · 2022Article
- Renal Recovery after the Implementation of an Electronic Alert and Biomarker-Guided Kidney-Protection Strategy following Major Surgery.Journal of clinical medicine · 2021Article
- Association Between the Central Venous Pressure and All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury.International journal of general medicine · 2021Article
- Body Mass Index Is Associated with the Severity and All-Cause Mortality of Acute Kidney Injury in Critically Ill Patients: An Analysis of a Large Critical Care Database.BioMed research international · 2021Article
- Relationship between platelet/lymphocyte ratio and prognosis of patients with septic acute kidney injury: A pilot study.Journal of the Chinese Medical Association : JCMA · 2020Article
- Serum Anion Gap Predicts All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury: Analysis of the MIMIC-III Database.Disease markers · 2020Article
- Quality of life following hospitalization-associated acute kidney injury in children.Journal of nephrology · 2018Article
- The Japanese Clinical Practice Guideline for acute kidney injury 2016.Journal of intensive care · 2018Article
- Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference.Annals of intensive care · 2017Review
- Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury.Critical care (London, England) · 2017Article
- The predictive value of early acute kidney injury for long-term survival and quality of life of critically ill patients.Critical care (London, England) · 2016Article
- Long-term quality of life in critically ill patients with acute kidney injury treated with renal replacement therapy: a matched cohort study.Critical care (London, England) · 2015Article
- Acute kidney injury-epidemiology, outcomes and economics.Nature reviews. Nephrology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcute kidney injury (AKI) is a serious complication in critically ill patients admitted to the Intensive Care Unit (ICU). We hypothesized that ICU survivors with AKI would have a worse health-related quality of life (HRQOL) outcome than ICU survivors without AKI.
methodsWe performed a long-term prospective observational study. Patients admitted for > 48 hours in a medical-surgical ICU were included and divided in two groups: patients who fulfilled RIFLE criteria for AKI and patients without AKI. We used the Short-Form 36 to evaluate HRQOL before admission (by proxy within 48 hours after admission of the patient), at ICU discharge, hospital discharge, 3 and 6 months following ICU discharge (all by patients). Recovery in HRQOL from ICU-admission onwards was assessed using linear mixed modelling.
resultsBetween September 2000 and January 2007 all admissions were screened for study participation. We included a total of 749 patients. At six months after ICU discharge 73 patients with AKI and 325 patients without AKI could be evaluated. In survivors with and without AKI, the pre-admission HRQOL (by proxy) and at six months after ICU discharge was significantly lower compared with an age matched general population. Most SF-36 dimensions changed significantly over time from ICU discharge. Change over time of HRQOL between the different AKI Rifle classes (Risk, Injury, Failure) showed no significant differences. At ICU discharge, scores were lowest in the group with AKI compared with the group without AKI for the physical functioning, role-physical and general health dimensions. However, there were almost no differences in HRQOL between both groups at six months.
conclusionsThe pre-admission HRQOL (by proxy) of AKI survivors was significantly lower in two dimensions compared with the age matched general population. Six months after ICU discharge survivors with and without AKI showed an almost similar HRQOL. However, compared with the general population with a similar age, HRQOL was poorer in both groups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.