Trial reportPloS one2013
Comparison of the distal gut microbiota from people and animals in Africa.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Urbanization gradient, diet, and gut microbiota in Sub-Saharan Africa: a systematic review.Frontiers in microbiomes · 2023Pooled it
- Bacterial fecal microbiome composition associated with HIV stage among rural and peri-urban adults living with HIV in Uganda.BMC infectious diseases · 2026Article
- Using culture 'omics to explore the microbial structure and function in an equid in vitro digestion model.Scientific reports · 2025Article
- Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans.Animal microbiome · 2025Article
- The Impact of the Lactation Period Gut Microbiota of Two Different Beef Cattle Breeds on Spring-Born Calves.Animals : an open access journal from MDPI · 2025Article
- Early-life gut bacterial community structure predicts disease risk and athletic performance in horses bred for racing.Scientific reports · 2024Article
- 16S rRNA gene amplicon sequencing data from the gut microbiota of adolescent Afghan refugees.Data in brief · 2024Article
- Review
- NMR Metabolomics and DNA Sequencing ofMetabolites · 2023Article
- Impact of inorganic iron and haem on the human gut microbiota; AnFrontiers in microbiology · 2023Article
- Effect of Dietary Lactose Supplementation on Growth Performance and Intestinal Epithelium Functions in Weaned Pigs Challenged by Rotavirus.Animals : an open access journal from MDPI · 2022Article
- The Impact of ProbioticAnimals : an open access journal from MDPI · 2022Review
- Interplay between Bacterial Clones and Plasmids in the Spread of Antibiotic Resistance Genes in the Gut: Lessons from a Temporal Study in Veal Calves.Applied and environmental microbiology · 2021Article
- Changes in the Nasal Microbiota of Pigs Following Single or Co-Infection with Porcine Reproductive and Respiratory Syndrome and Swine Influenza A Viruses.Pathogens (Basel, Switzerland) · 2021Article
- Microbial Diversity Profiling of Gut Microbiota ofMicroorganisms · 2021Article
- Effects of in vitro metabolism of a broccoli leachate, glucosinolates and S-methylcysteine sulphoxide on the human faecal microbiome.European journal of nutrition · 2021Article
- Bugs and drugs: a systems biology approach to characterising the effect of moxidectin on the horse's faecal microbiome.Animal microbiome · 2020Article
- Microbial transmission in animal social networks and the social microbiome.Nature ecology & evolution · 2020Review
- The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography.The ISME journal · 2020Article
- The day-to-day stability of the ruminal and fecal microbiota in lactating dairy cows.MicrobiologyOpen · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The gut microbiota plays a key role in the maintenance of healthy gut function as well as many other aspects of health. High-throughput sequence analyses have revealed the composition of the gut microbiota, showing that there is a core signature to the human gut microbiota, as well as variation in its composition between people. The gut microbiota of animals is also being investigated. We are interested in the relationship between bacterial taxa of the human gut microbiota and those in the gut microbiota of domestic and semi-wild animals. While it is clear that some human gut bacterial pathogens come from animals (showing that human--animal transmission occurs), the extent to which the usually non-pathogenic commensal taxa are shared between humans and animals has not been explored. To investigate this we compared the distal gut microbiota of humans, cattle and semi-captive chimpanzees in communities that are geographically sympatric in Uganda. The gut microbiotas of these three host species could be distinguished by the different proportions of bacterial taxa present. We defined multiple operational taxonomic units (OTUs) by sequence similarity and found evidence that some OTUs were common between human, cattle and chimpanzees, with the largest number of shared OTUs occurring between chimpanzees and humans, as might be expected with their close physiological similarity. These results show the potential for the sharing of usually commensal bacterial taxa between humans and other animals. This suggests that further investigation of this phenomenon is needed to fully understand how it drives the composition of human and animal gut microbiotas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.