ArticleFrontiers in human neuroscience2013
Dopaminergic foundations of schizotypy as measured by the German version of the Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE)-a suitable endophenotype of schizophrenia.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Psychometric properties of the schizotypal personality questionnaire-brief revised (SPQ-BR) in a German-speaking sample.Scientific reports · 2026Article
- The Relationship Between Schizotypal Personality Traits and Temporal Discounting: The Role of the Date/Delay Effect.Schizophrenia bulletin · 2025Article
- Amygdala Function, Blood Flow, and Functional Connectivity in Nonclinical Schizotypy.Schizophrenia bulletin · 2025Article
- An exploratory network analysis to investigate schizotypy's structure using the 'Multidimensional Schizotypy Scale' and 'Oxford-Liverpool Inventory' in a healthy cohort.Schizophrenia (Heidelberg, Germany) · 2025Article
- Schizotypal Traits in College Students: Association with Empathy and Psychiatric Symptoms.Cureus · 2024Article
- Dopaminergic Epistases in Schizophrenia.Brain sciences · 2024Review
- Sleep Matters in Chronotype and Mental Health Association: Evidence from the UK and Germany.Brain sciences · 2024Article
- How to elicit a negative bias? Manipulating contrast and saturation with the facial emotion salience task.Frontiers in psychology · 2024Article
- Schizophrenia polygenic risk score in psychosis proneness.European archives of psychiatry and clinical neuroscience · 2023Article
- Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization.European archives of psychiatry and clinical neuroscience · 2023Article
- Neural Correlates of Smooth Pursuit Eye Movements in Schizotypy and Recent Onset Psychosis: A Multivariate Pattern Classification Approach.Schizophrenia bulletin open · 2022Article
- Distress severity in perceptual anomalies moderates the relationship between prefrontal brain structure and psychosis proneness in nonclinical individuals.European archives of psychiatry and clinical neuroscience · 2021Article
- The network structure of schizotypy in the general population.European archives of psychiatry and clinical neuroscience · 2021Article
- Schizotypy in Parkinson's disease predicts dopamine-associated psychosis.Scientific reports · 2021Article
- An Inventory of Problems-29 (IOP-29) study investigating feigned schizophrenia and random responding in a British community sample.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2021Article
- Cognitive Gain or Handicap: Magical Ideation and Self-Absorption in Clinical and Non-clinical Participants.Frontiers in psychology · 2021Article
- Relationship between behavioral measures of anxiety and latent inhibition in mature rats.Learning & behavior · 2019Article
- Models of Schizotypy: The Importance of Conceptual Clarity.Schizophrenia bulletin · 2018Review
- Assessment of Cognition and Personality as Potential Endophenotypes in the Western Australian Family Study of Schizophrenia.Schizophrenia bulletin · 2018Article
- Depressive symptoms are associated with poor sleep quality rather than apnea-hypopnea index or hypoxia during sleep in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2017Article
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Abstract
The concept of schizotypy or "psychosis proneness" captures individual differences in perceptual, cognitive, and affective experiences that may relate to a range of psychotic disorders. The concept is an important way to assess the contribution of pre-existing psychological and genetically based biological features to the development of illnesses such as schizophrenia (so called endophenotypes). The Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE) is a widely used multi-dimensional measure of the construct and consists of four scales which mirror several groups of psychotic symptoms: Unusual Experiences (UnEx; positive symptoms), Cognitive Disorganization (CogDis; cognitive symptoms), Introvertive Anhedonia (IntAn; negative symptoms), and Impulsive Nonconformity (ImpNon; impulsive and antisocial symptoms). For the purpose of evaluating the suitability of schizotypy as an endophenotype of schizophrenia the current version of the O-LIFE was translated into German: its psychometric properties (including re-test reliability and construct validity) were examined in a large sample (n > 1200) and compared to those of the English original. The German version was both highly reliable and consistent with the original. The study aimed to show that schizotypy as measured by the O-LIFE can indeed be regarded as an endophenotype of schizophrenia in terms of genetic associations regarding relevant dopamine-related candidate polymorphisms of schizotypy [i.e., Val(158)Met-polymorphism of the COMT gene, uVNTR of the MAOA gene, Taq1A-polymorphism of the DRD2 gene, VNTR of the SLC6A3 (DAT) gene]. We also wanted to compare the genetic associations of the O-LIFE to those published using other operationalizations of schizotypy. Our results show a large number of significant associations and borderline-significant trends between the O-LIFE sub-scales and a range of genes, thereby supporting using the O-LIFE in the search for endophenotypic markers.
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