Evidence map›Paper›PMID 23355273›Full record

Trial reportCancer2013

An eHealth system supporting palliative care for patients with non-small cell lung cancer: a randomized trial.

David H Gustafson, Lori L DuBenske, Kang Namkoong, Robert Hawkins, Ming-Yuan Chih, Amy K Atwood, Roberta Johnson, Abhik Bhattacharya, Cindy L Carmack, Anne M Traynor and 5 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04159363 (The Effectiveness of an Interactive Colorectal Cancer Self-Management Enhancement Smartphone-based Psychosocial Intervention Programme), which is not on this map. Cited by 55 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04159363 naunknown statusnot on this mapstarted 2020, after this paper: background citation

The Effectiveness of an Interactive Colorectal Cancer Self-Management Enhancement Smartphone-based Psychosocial Intervention Programme (iCanManage) on Outcomes of Patients With Colorectal Cancer and Their Family Caregivers

TypeinterventionalSponsorSingapore Cancer SocietyRan2020 to 2021Enrolled200ConditionsColorectal CancerArmsAn interactive Colorectal Cancer self-Management enhancement smartphone-based psychosocial intervention programme (iCanManage)
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Effect of applying digital health in palliative care for patients with advanced cancer: a meta-analysis and systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Effectiveness of Skill-Building Interventions for Informal Caregivers of Adults with Cancer: a Systematic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
    Pooled it
  3. Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

David H GustafsonCenter for Health Enhancement Systems Studies, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA. dhgustaf@wisc.edu
Lori L DuBenske
Kang Namkoong
Robert Hawkins
Ming-Yuan Chih
Amy K Atwood
Roberta Johnson
Abhik Bhattacharya
Cindy L Carmack
Anne M Traynor
Toby C Campbell
Mary K Buss
Ramaswamy Govindan
Joan H Schiller
James F Cleary

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Using Technology to Enhance Cancer Communication and Improve Clinical OutcomesP50CA095817 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI GUSTAFSON, DAVID H · 2003 to 2012
$19.3M
NCI NIH HHS P30 CA014520NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA095817
6 · The paper itself

Abstract

backgroundIn this study, the authors examined the effectiveness of an online support system (Comprehensive Health Enhancement Support System [CHESS]) versus the Internet in relieving physical symptom distress in patients with non-small cell lung cancer (NSCLC).

methodsIn total, 285 informal caregiver-patient dyads were assigned randomly to receive, for up to 25 months, standard care plus training on and access to either use of the Internet and a list of Internet sites about lung cancer (the Internet arm) or CHESS (the CHESS arm). Caregivers agreed to use CHESS or the Internet and to complete bimonthly surveys; for patients, these tasks were optional. The primary endpoint-patient symptom distress-was measured by caregiver reports using a modified Edmonton Symptom Assessment Scale.

resultsCaregivers in the CHESS arm consistently reported lower patient physical symptom distress than caregivers in the Internet arm. Significant differences were observed at 4 months (P = .031; Cohen d = .42) and at 6 months (P = .004; d = .61). Similar but marginally significant effects were observed at 2 months (P = .051; d = .39) and at 8 months (P = .061; d = .43). Exploratory analyses indicated that survival curves did not differ significantly between the arms (log-rank P = .172), although a survival difference in an exploratory subgroup analysis suggested an avenue for further study.

conclusionsThe current results indicated that an online support system may reduce patient symptom distress. The effect on survival bears further investigation.

Indexed as

InternetPalliative CareAdultAgedCarcinoma, Non-Small-Cell LungCaregiversHumansLung NeoplasmsMiddle Aged

Identifiers

PMID23355273
PMCPMC3684251

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.