Evidence map›Paper›PMID 23355182›Full record

Trial reportCancer2013

Qigong improves quality of life in women undergoing radiotherapy for breast cancer: results of a randomized controlled trial.

Zhen Chen, Zhiqiang Meng, Kathrin Milbury, Wenying Bei, Ying Zhang, Bob Thornton, Zhongxing Liao, Qi Wei, Jiayi Chen, Xiaoma Guo and 4 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 38 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 38 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 38 syntheses or guidelines pooled it, 158 citations in OpenAlex.

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  20. Impact on fatigue of different types of physical exercise during adjuvant chemotherapy and radiotherapy in breast cancer: systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Zhen ChenDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhiqiang Meng
Kathrin Milbury
Wenying Bei
Ying Zhang
Bob Thornton
Zhongxing Liao
Qi Wei
Jiayi Chen
Xiaoma Guo
Luming Liu
Jennifer McQuade
Clemens Kirschbaum
Lorenzo Cohen
Fudan University Shanghai Cancer Center · CNThe University of Texas MD Anderson Cancer Center · USHospital of the University of Pennsylvania · USTU Dresden · DE

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
R25 SUPPLEMENT IN GENETIC EPIDEMIOLOGY EDUCATIONR25CA057730 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHANG, SHINE · 1992 to 2016
$18.6M
International Center of TCM for CancerU19CA121503 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2005 to 2010
$3.0M
Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersK01AT007559 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2013 to 2017
$652k
International Center of TCM for CancerR21CA108084 · NCI · UNIVERSITY OF TEXAS MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2003 to 2004
$263k
NCCIH NIH HHS K01 AT007559NCI NIH HHS CA016672NCI NIH HHS P30 CA016672NCI NIH HHS R21 CA108084NCI NIH HHS R21CA108084NCI NIH HHS R25 CA057730NCI NIH HHS U19 CA121503NCI NIH HHS U19CA121503
6 · The paper itself

Abstract

backgroundRadiotherapy may lead to side effects that undermine patients' quality of life (QOL). Although mind-body practices like qigong appear to improve QOL in cancer survivors, little is known about their benefits for patients who are receiving radiotherapy. Thus, in the current randomized controlled trial, the authors examined the efficacy of a qigong intervention on QOL in women with breast cancer during and after treatment.

methodsNinety-six women with breast cancer were recruited from a cancer center in Shanghai, China, and were randomized to a qigong group (N = 49) or a waitlist control group (N = 47). Women in the qigong group attended 5 weekly classes over 5 or 6 weeks of radiotherapy. QOL outcomes (ie, depressive symptoms, fatigue, sleep disturbance, and overall QOL) and cortisol slopes were assessed at baseline, during treatment, at the end of treatment, 1 month later, and 3 months later.

resultsThe mean age of the women was 46 years (range, 25-64 years). Seven percent of women had stage 0 disease, 25% had stage I disease, 40% had stage II disease, and 28% had stage III disease. Fifty-four percent of women underwent mastectomy. Multilevel analyses revealed that women in the qigong group reported less depressive symptoms over time than women in the control group (P = .05). Women who had elevated depressive symptoms at the start of radiotherapy reported less fatigue (P < .01) and better overall QOL (P < .05) in the qigong group compared with the control group, and these findings were clinically significant. No significant differences were observed for sleep disturbance or cortisol slopes.

conclusionsThe current results indicated that qigong may have therapeutic effects in the management of QOL among women who are receiving radiotherapy for breast cancer. Benefits were particularly evident for patients who had preintervention elevated levels of depressive symptoms.

Indexed as

Breathing ExercisesQuality of LifeAdultBreast NeoplasmsFatigueFemaleHumansHydrocortisoneMiddle AgedPatient ComplianceSleep Wake DisordersWaiting ListsHydrocortisone

Identifiers

PMID23355182
PMCPMC3852682
OpenAlexW1985032321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.