Evidence map›Paper›PMID 23355109›Full record

ReviewCA: a cancer journal for clinicians2013

Risk factors, pathophysiology, and treatment of hot flashes in cancer.

William I Fisher, Aimee K Johnson, Gary R Elkins, Julie L Otte, Debra S Burns, Menggang Yu, Janet S Carpenter

Open access · diamondAbstract readReview
In one paragraph

Review in CA: a cancer journal for clinicians, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. MsFLASH participants' priorities for alleviating menopausal symptoms.Climacteric : the journal of the International Menopause Society · 2015
    Trial
  6. Article
  7. Article
  8. Article
  9. Establishment of stellate ganglion block in mice.European journal of medical research · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Breast cancer (Dove Medical Press) · 2017
    Article
  18. Article
  19. Complementary and Alternative Medicine for Menopause.Journal of evidence-based integrative medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

William I FisherDepartment of Psychology and Neuroscience, Baylor University, Waco, TX, USA.
Aimee K Johnson
Gary R Elkins
Julie L Otte
Debra S Burns
Menggang Yu
Janet S Carpenter
Baylor University · USIndiana University – Purdue University Indianapolis · USUniversity of Wisconsin–Madison · US

Funding

Hypnosis for Hot Flashes: A Randomized Clinical TrialU01AT004634 · NCCIH · BAYLOR UNIVERSITY · PI ELKINS, GARY R · 2007 to 2011
$2.5M
Breathe-Intervention for Hot Flashes, Interference, and Associated OutcomesR01CA132927 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CARPENTER, JANET S · 2008 to 2011
$1.2M
NCCIH NIH HHS U01 AT004634NCI NIH HHS 5 R01 CA132927NCI NIH HHS R01 CA132927
6 · The paper itself

Abstract

Hot flashes are prevalent and severe symptoms that can interfere with mood, sleep, and quality of life for women and men with cancer. The purpose of this article is to review existing literature on the risk factors, pathophysiology, and treatment of hot flashes in individuals with cancer. Electronic searches were conducted to identify relevant English-language literature published through June 15, 2012. Results indicated that risk factors for hot flashes in cancer include patient-related factors (eg, age, race/ethnicity, educational level, smoking history, cardiovascular risk including body mass index, and genetics) and disease-related factors (eg, cancer diagnosis and dose/type of treatment). In addition, although the pathophysiology of hot flashes has remained elusive, these symptoms are likely attributable to disruptions in thermoregulation and neurochemicals. Therapies that have been offered or tested fall into 4 broad categories: pharmacological, nutraceutical, surgical, and complementary/behavioral strategies. The evidence base for this broad range of therapies varies, with some treatments not yet having been fully tested or showing equivocal results. The evidence base surrounding all therapies is evaluated to enhance hot flash treatment decision-making by clinicians and patients.

Indexed as

Adrenergic AntagonistsAnticonvulsantsAntidepressive AgentsAutonomic Nerve BlockBody Temperature RegulationCholinergic AntagonistsCognitive Behavioral TherapyComplementary TherapiesHot FlashesHumansNeoplasmsPhytotherapyRisk FactorsStellate GanglionVitaminsAdrenergic AntagonistsAnticonvulsantsAntidepressive AgentsCholinergic AntagonistsVitamins

Identifiers

PMID23355109
PMCPMC3640615
OpenAlexW2077096111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.