ArticleApplied and environmental microbiology2013
Genetic diversity of Cryptosporidium spp. within a remote population of Soay Sheep on St. Kilda Islands, Scotland.
Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Cryptosporidium infections in terrestrial ungulates with focus on livestock: a systematic review and meta-analysis.Parasites & vectors · 2019Pooled it
- Examination of ELISA against PCR for assessing treatment efficacy against Cryptosporidium in a clinical trial context.PloS one · 2023Trial
- Molecular Epidemiology of Cryptosporidiosis on Lamb and Goat Kid Farms in Gran Canaria, Canary Islands (Spain).Microorganisms · 2025Article
- Coproantigen detection and molecular identification of Cryptosporidium species among newborn and adult farm animals.AMB Express · 2025Article
- Genetic diversity ofCurrent research in parasitology & vector-borne diseases · 2025Article
- Diverse Genotypes ofPathogens (Basel, Switzerland) · 2022Article
- Small ruminants and zoonotic cryptosporidiosis.Parasitology research · 2021Review
- Prevalence and distribution pattern of Cryptosporidium spp. among pre-weaned diarrheic calves in the Republic of Korea.PloS one · 2021Article
- Sheep as a Potential Source of Zoonotic Cryptosporidiosis in China.Applied and environmental microbiology · 2018Article
- Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum.International journal for parasitology · 2017Article
- Diversity of Cryptosporidium species occurring in sheep and goat breeds reared in Poland.Parasitology research · 2017Article
- Molecular investigation of Cryptosporidium in small caged pets in northeast China: host specificity and zoonotic implications.Parasitology research · 2016Article
- Exposure to viral and bacterial pathogens among Soay sheep (Ovis aries) of the St Kilda archipelago.Epidemiology and infection · 2016Article
- Prevalence of Cryptosporidium in small ruminants from Veracruz, Mexico.BMC veterinary research · 2016Article
- Cryptosporidium species and subtype analysis in diarrhoeic pre-weaned lambs and goat kids from north-western Spain.Parasitology research · 2015Article
- Prevalence of Cryptosporidium infection in captive lesser panda (Ailurus fulgens) in China.Parasitology research · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This is the first report to characterize the genotypes and subtypes of Cryptosporidium species infecting a geographically isolated population of feral Soay sheep (Ovis aries) on Hirta, St. Kilda, Scotland, during two distinct periods: (i) prior to a population crash and (ii) as host numbers increased. Cryptosporidium DNA was extracted by freeze-thawing of immunomagnetically separated (IMS) bead-oocyst complexes, and species were identified following nested-PCR-restriction fragment length polymorphism (RFLP)/PCR sequencing at two Cryptosporidium 18S rRNA loci. Two hundred fifty-five samples were analyzed, and the prevalent Cryptosporidium species in single infections were identified as C. hominis (11.4% of all samples tested), C. parvum (9%), C. xiaoi (12.5%), and C. ubiquitum (6.7%). Cryptosporidium parvum was also present with other Cryptosporidium species in 27.1% of all samples tested. Cryptosporidium parvum- and C. hominis-positive isolates were genotyped using two nested-PCR assays that amplify the Cryptosporidium glycoprotein 60 gene (GP60). GP60 gene analysis showed the presence of two Cryptosporidium genotypes, namely, C. parvum IIaA19G1R1 and C. hominis IbA10G2. This study reveals a higher diversity of Cryptosporidium species/genotypes than was previously expected. We suggest reasons for the high diversity of Cryptosporidium parasites within this isolated population and discuss the implications for our understanding of cryptosporidiosis.
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