ReviewDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2013
[Effect of resveratrol on the fundus oculi. An overview].
Review in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resveratrol is a polyphenol with various properties. Oncological studies have shown an excellent anti-carcinogenic effect. Due to many overlaps between tumor-mediating signaling pathways and those which mediate neovascularization and proliferation in retinal diseases, this review intends to focus on studies about the application of resveratrol in diseases of the eye fundus in vitro and in vivo. Resveratrol has been well investigated in cell culture studies and animal models. Ophthalmological in vitro and in vivo investigations have shown a large variety of possible effects without toxic side effects and antiproliferative and immune modulatory effects in particular were observed. There is general consensus that the target protein of resveratrol is NF-κB. Clinical studies are needed to confirm these effects observed in cell culture and animal models. The exact mechanism of resveratrol remains unknown and seems to vary between cell types, tissues and the pathophysiological environment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.