ArticleRNA biology2013
Lifelong companions: RNA helicases and their roles in RNA metabolism.
Article in RNA biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- The DEAD-Box Protein Rok1 Coordinates Ribosomal RNA Processing in Association with Rrp5 inInternational journal of molecular sciences · 2022Article
- A DEAD-box protein acts through RNA to promote HIV-1 Rev-RRE assembly.Nucleic acids research · 2017Article
- The DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation.PLoS biology · 2016Article
- RNA Helicase Important for Listeria monocytogenes Hemolytic Activity and Virulence Factor Expression.Infection and immunity · 2016Article
- HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.PLoS pathogens · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The life of an RNA molecule is complicated. Once a newly synthesized eukaryotic RNA has emerged from the RNA polymerase in the nucleus, it will be processed, spliced, and exported into cytoplasm. In prokaryotes, transcribed RNA is synthesized directly in the cytoplasm. RNA molecules that serve as mRNAs have to be kept devoid of local structures that are inhibitory for ribosome scanning and translation. Quite differently, structural and catalytic RNAs have to adopt a defined three-dimensional conformation to exert their biological function, and may assemble with other protein and/or RNA partners into complex functional units. Ultimately, RNA degradation by the so-called degradosome will end the RNA's life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.