Evidence map›Paper›PMID 23352646›Full record

ArticleCancer letters2013

Mesenchymal and stem-like cell properties targeted in suppression of chronically-induced breast cell carcinogenesis.

Kusum Rathore, Hwa-Chain Robert Wang

Abstract read
In one paragraph

Article in Cancer letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kusum RathoreDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN 37996, USA.
Hwa-Chain Robert Wang

Funding

Green tea catechins in precancerorus preventionR21CA129772 · NCI · UNIVERSITY OF TENNESSEE KNOXVILLE · PI WANG, HWA-CHAIN ROBERT · 2008 to 2009
$353k
Carcinogenesis cellular model for identifying preventive agentsR03CA125795 · NCI · UNIVERSITY OF TENNESSEE KNOXVILLE · PI WANG, HWA-CHAIN ROBERT · 2007 to 2008
$145k
NCI NIH HHS CA125795NCI NIH HHS CA129772NCI NIH HHS R03 CA125795NCI NIH HHS R21 CA129772
6 · The paper itself

Abstract

Stem-like cells and the epithelial-to-mesenchymal transition (EMT) program are postulated to play important roles in various stages of cancer development, but their roles in breast cell carcinogenesis and intervention remain to be clarified. We investigated stem-like cell- and EMT-associated properties and markers in breast epithelial cells chronically exposed to low-dose 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene in the presence and absence of the preventive agents green tea catechins and grape seed extract. Our results indicate that stem-like cell- and EMT-associated properties and markers should be seriously considered as new cancer-associated indicators for detecting breast cell carcinogenesis and as endpoints for intervention of carcinogenesis.

Indexed as

Cell Transformation, NeoplasticBenzo(a)pyreneBreast NeoplasmsCatechinEpithelial-Mesenchymal TransitionFemaleGrape Seed ExtractHumansNitrosaminesProanthocyanidinsStem CellsTea4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneBenzo(a)pyreneCatechinGrape Seed ExtractGrape Seed ProanthocyanidinsNitrosaminesProanthocyanidinsTea

Identifiers

PMID23352646
PMCPMC3628412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.