Evidence map›Paper›PMID 23352524›Full record

Trial reportAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2013

Asthma medication adherence: the role of God and other health locus of control factors.

Brian K Ahmedani, Edward L Peterson, Karen E Wells, Cynthia S Rand, L Keoki Williams

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00459368 (Adherence Feedback for Improving Respiratory Medication Use), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00459368 nacompletednot on this map

Adherence Feedback for Improving Respiratory Medication Use

TypeinterventionalSponsorHenry Ford Health SystemRan2007 to 2009Enrolled2,698ConditionsAsthma, Patient ComplianceArmsFeedback of patient adherence information, Active control group
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions to improve adherence to inhaled steroids for asthma.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brian K AhmedaniCenter for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA. bahmeda1@hfhs.org
Edward L Peterson
Karen E Wells
Cynthia S Rand
L Keoki Williams

Funding

PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMAR01AI079139 · NIAID · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2009 to 2013
$3.9M
Mechanism of Endotoxin's Effect On Allergy RiskR01AI061774 · NIAID · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2004 to 2008
$2.9M
VALIDATION OF ADHERENCE DATA--USE IN CLINICAL PRACTICER01DK064695 · NIDDK · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2003 to 2010
$2.7M
USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCER01HL079055 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2005 to 2008
$1.4M
NHLBI NIH HHS R01 HL079055NHLBI NIH HHS R01HL079055NIAID NIH HHS R01 AI061774NIAID NIH HHS R01AI061774NIAID NIH HHS R01 AI079139NIAID NIH HHS R01AI079139NIDDK NIH HHS R01 DK064695NIDDK NIH HHS R01DK064695
6 · The paper itself

Abstract

backgroundMedication adherence is an important determinant of disease outcomes, yet medication use on average tends to be low among patients with chronic conditions, including asthma. Although several predictors of non-adherence have been assessed, more research is needed on patients' beliefs about God and how these relate to medication use.

objectiveTo examine the relationship between perceptions about "God's" role in health and other locus of control factors with inhaled corticosteroid (ICS) adherence among asthma patients.

methodsParticipants were from a clinical trial to improve ICS adherence and were 5-56 years old, had a diagnosis of asthma, and were receiving ICS medication. Baseline adherence was estimated from electronic prescription and pharmacy fill records. Patients were considered to be adherent if ICS use was ≥80% of prescribed. A baseline survey with the Multidimensional Health Locus of Control scale was used to assess five sources (God, doctors, other people, chance, and internal).

resultsMedication adherence was low (36%). Patients' who had a stronger belief that God determined asthma control were less likely to be adherent (odds ratio [OR] 0.82, 95% confidence interval [CI] 0.70-0.96). This relationship was stronger among African American (OR 0.68, 95% CI0.47-0.99) compared to white patients (OR 0.89, 95% CI 0.75-1.04), and among adults (OR 0.81, 95% CI 0.69-0.96) compared to children (OR 0.84, 95% CI 0.58-1.22).

conclusionPatients' belief in God's control of health appears to be a factor in asthma controller use, and therefore should be considered in physician-patient discussions concerning course of treatment.

trial registrationClinicalTrials.gov: NCT00459368.

Indexed as

ReligionAdolescentAdultAsthmaChildChild, PreschoolFemaleHumansMaleMedication AdherenceMiddle Aged

Identifiers

PMID23352524
PMCPMC3558920

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.