ArticleParasites & vectors2013
A flea and tick collar containing 10% imidacloprid and 4.5% flumethrin prevents flea transmission of Bartonella henselae in cats.
Article in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 45 citations in OpenAlex.
- Field comparison of tolerance of a collar containing 10.0% imidacloprid/4.5% flumethrin (Seresto) and a placebo collar placed on cats.Journal of feline medicine and surgery · 2016Trial
- Evaluation and comparison of a flumethrin-imidacloprid collar and repeated monthly treatments of fipronil/(s)-methoprene to control flea, Ctenocephalides f. felis, infestations on cats for eight months.Parasites & vectors · 2016Trial
- Comparative Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and an Oral Afoxolaner Chewable (NexGard®) against Tick (Dermacentor variabilis and Amblyomma americanum) Infestations on Dogs: a Randomised Controlled Trial.Parasitology research · 2015Trial
- Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs.Parasites & vectors · 2013Trial
- Highlighting zoonotic importance of synanthropic fleas through microbiome analysis.Scientific reports · 2025Article
- Experimental Infection of Ferrets withPathogens (Basel, Switzerland) · 2025Article
- Pradofloxacin for Treatment ofPathogens (Basel, Switzerland) · 2024Article
- Epidemiology of Bartonella henselae infection in pet and stray cats in Croatia with risk factors analysis.Parasites & vectors · 2024Article
- Prevalence and Risk Factors forVeterinary sciences · 2022Article
- Aspects in controlled drug delivery for topical applications in veterinary medicine.Veterinary and animal science · 2022Article
- Using Proteomic Approaches to Unravel the Response ofFrontiers in cellular and infection microbiology · 2022Article
- Exposure of Domestic Cats to Three ZoonoticPathogens (Basel, Switzerland) · 2021Article
- Bartonella species in medically important mosquitoes, Central Europe.Parasitology research · 2020Article
- Role of vector-borne pathogens in the development of fever in cats: 1. Flea-associated diseases.Journal of feline medicine and surgery · 2020Review
- Detection of Bartonella spp. in dogs after infection with Rickettsia rickettsii.Journal of veterinary internal medicine · 2020Article
- 2019 AAFP Feline Zoonoses Guidelines.Journal of feline medicine and surgery · 2019Article
- Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats.Parasites & vectors · 2019Article
- Bartonella infections in cats and dogs including zoonotic aspects.Parasites & vectors · 2018Review
- The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review.Insects · 2017Review
- Bartonella spp. - a chance to establish One Health concepts in veterinary and human medicine.Parasites & vectors · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBartonella henselae is transmitted amongst cats by Ctenocephalides felis and is associated with multiple clinical syndromes in cats and people. In a previous study, monthly spot-on administration of 10% imidacloprid/1% moxidectin was shown to block transmission of B. henselae amongst cats experimentally exposed to infected C. felis. The purpose of this study was to determine whether application of a flea and tick collar containing 10% imidacloprid and 4.5% flumethrin would lessen C. felis transmission of B. henselae amongst cats for 8 months.
methodsSpecific pathogen free cats (n = 19) were housed in three adjoining enclosures that were separated by mesh to allow C. felis to pass among groups but prevent cats in different enclosures from contacting one another. One group of 4 cats was inoculated intravenously with B. henselae and after infection was confirmed in all cats based on positive PCR assay results, the cats were housed in the middle enclosure. The B. henselae infected cat group was flanked by a group of 8 cats that had the collar placed and maintained for the duration of the study and a group of 7 cats that were not treated. Ctenocephalides felis (50 males and 50 females) raised in an insectary were placed on each of the 4 cats in the B. henselae infected group monthly for 7 applications and then every 2 weeks for 4 applications starting the day the collar was applied. Blood was collected from all cats weekly for Bartonella spp. PCR, serology and culture.
resultsWhile side-effects associated with the collars were not noted, persistent fever necessitating enrofloxacin therapy occurred in two of the untreated cats. While B. henselae infection was ultimately confirmed in 4 of 7 of the untreated cats, none of the cats with collars became infected (P = 0.026).
conclusionsIn this study design, use of a collar containing 10% imidacloprid and 4.5% flumethrin was well tolerated and prevented C. felis transmission of B. henselae amongst cats for 8 months.
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Registered trials
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