Evidence map›Paper›PMID 23351709›Full record

ReviewInternational review of cell and molecular biology2013

Molecular insights into intracellular RNA localization.

Michael D Blower

Open access · greenAbstract readReview
In one paragraph

Review in International review of cell and molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Zebrafish crocc2 mutants exhibit divergent craniofacial shape, misregulated variability, and aberrant cartilage morphogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. RNA biology · 2021
    Article
  10. What defines the maternal transcriptome?Biochemical Society transactions · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. A light way for nuclear cell biologists.Journal of biochemistry · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael D BlowerDepartment of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA, USA. blower@molbio.mgh.harvard.edu
Center for Systems Biology · US

Funding

Analysis of microtubule localized RNAsR01GM086434 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BLOWER, MICHAEL DEMIAN · 2009 to 2013
$1.6M
NIGMS NIH HHS 5 R01 GM086434-05NIGMS NIH HHS R01 GM086434
6 · The paper itself

Abstract

Localization of mRNAs to specific destinations within a cell or an embryo is important for local control of protein synthesis. mRNA localization is well known to function in very large and polarized cells such as neurons, and to facilitate embryonic patterning during early development. However, recent genome-wide studies have revealed that mRNA localization is more widely utilized than previously thought to control gene expression. Not only can transcripts be localized asymmetrically within the cytoplasm, they are often also localized to symmetrically distributed organelles. Recent genetic, cytological, and biochemical studies have begun to provide molecular insight into how cells select RNAs for transport, move them to specific destinations, and control their translation. This chapter will summarize recent insights into the mechanisms and function of RNA localization with a specific emphasis on molecular insights into each step in the mRNA localization process.

Indexed as

AnimalsBiological Transport, ActiveBody PatterningCytoplasmEmbryonic DevelopmentGenome-Wide Association StudyHumansNeuronsRNA, MessengerRNA, Messenger

Identifiers

PMID23351709
PMCPMC3746326
OpenAlexW1539977047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.