Evidence map›Paper›PMID 23351625›Full record

ArticleJournal of the Academy of Nutrition and Dietetics2013

The relationships between sugar-sweetened beverage intake and cardiometabolic markers in young children.

Ethan C Kosova, Peggy Auinger, Andrew A Bremer

Abstract read
In one paragraph

Article in Journal of the Academy of Nutrition and Dietetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 5 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 5 syntheses or guidelines pooled it, 147 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this map
    Guideline
  5. Determinants of sugar-sweetened beverage consumption in young children: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015
    Pooled it
  6. Trial
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  10. Article
  11. How does the Kids SIPAmerican journal of agricultural economics · 2026
    Article
  12. Article
  13. Review
  14. Difference-in-differences analysis with repeated cross-sectional survey data.Health services & outcomes research methodology · 2025
    Article
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  19. Observational
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ethan C KosovaDepartment of Medicine, Brigham and Women’s Hospital, Boston, MA, USA.
Peggy Auinger
Andrew A Bremer
Brigham and Women's Hospital · USUniversity of Rochester · USVanderbilt University · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
UC Davis Clinical and Translational Science CenterKL2RR024144 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$3.1M
NCRR NIH HHS KL2 RR024144NCRR NIH HHS UL1 RR024146NCRR NIH HHS UL1 RR024975NCRR NIH HHS UL1 RR024975-01
6 · The paper itself

Abstract

backgroundThe consumption of sugar-sweetened beverages has been implicated as a major contributor to the development of obesity and cardiometabolic disease.

objectiveTo evaluate the relationships between sugar-sweetened beverage intake and cardiometabolic markers in young children.

designA cross-sectional analysis of the National Health and Nutrition Examination Survey data collected by the National Center for Health Statistics.

participantsA total of 4,880 individuals aged 3 to 11 years from nationally representative samples of US children participating in the National Health and Nutrition Examination Survey during 1999-2004 were studied.

main outcome measuresConcentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, and C-reactive protein as well as waist circumference and body mass index percentile for age-sex. STATISTICAL ANALYSES PERFORMED: Multivariate linear regression analyses were performed to determine independent associations between each outcome variable and the number of serving equivalents of sugar-sweetened beverages consumed after adjusting for age, sex, race, poverty status, physical activity, and energy intake.

resultsIncreased sugar-sweetened beverage intake was independently associated with increased C-reactive protein concentrations (P=0.003), increased waist circumference (P=0.04), and decreased high-density lipoprotein cholesterol concentrations (P<0.001). Subgroup analyses demonstrated differences in the association of sugar-sweetened beverage intake with metabolic markers and anthropometric measurements among age ranges, sex, and racial/ethnic groups.

conclusionsIn this cross-sectional analysis of children's dietary data, sugar-sweetened beverage intake was independently associated with alterations in lipid profiles, increased markers of inflammation, and increased waist circumference in children. Prospective studies are needed, but awareness of these trends is essential in combating the growing metabolic and cardiovascular disease burden in the pediatric population.

Indexed as

Waist CircumferenceBeveragesBiomarkersBody Mass IndexCardiovascular DiseasesChildChild Nutritional Physiological PhenomenaChild, PreschoolCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinCross-Sectional StudiesDietary SucroseFemaleHumansBiomarkersCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinDietary SucroseSweetening AgentsTriglycerides

Identifiers

PMID23351625
PMCPMC4116486
OpenAlexW2019737126

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.