ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2012
Monitoring of adverse drug reactions associated with antihypertensive medicines at a university teaching hospital in New Delhi.
Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Adverse drug reaction (ADR) monitoring of antihypertensive drugs in a tertiary care setting: A prospective observational study.Bioinformation · 2025Article
- Acupuncture treatment for hypertension: a case study.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2014Article
- Retrospective evaluation of adverse drug reactions induced by antihypertensive treatment.Journal of pharmacology & pharmacotherapeutics · 2013Article
- Dual antihypertensive strategies: A real-world comparative study of efficacy and safety of fixed-dose combinations in a tertiary care setting.Perspectives in clinical researchArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
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aimTo monitor the adverse drug reactions (ADRs) caused by antihypertensive medicines prescribed in a university teaching hospital.
methodsThe present work was an open, non-comparative, observational study conducted on hypertensive patients attending the Medicine OPD of Majeedia Hospital, Jamia Hamdard, New Delhi, India by conducting patient interviews and recording the data on ADR monitoring form as recommended by Central Drugs Standard Control Organization (CDSCO), Government of India.
resultsA total of 21 adverse drug reactions were observed in 192 hypertensive patients. Incidence of adverse drug reactions was found to be higher in patients more than 40 years in age, and females experienced more ADRs (n = 14, 7.29%) than males, 7 (3.64%). Combination therapy was associated with more number of adverse drug reactions (66.7%) as against monotherapy (33.3%). Calcium channel blockers were found to be the most frequently associated drugs with adverse drug reactions (n = 7), followed by diuretics (n = 5), and β-blockers (n = 4). Among individual drugs, amlodipine was found to be the commonest drug associated with adverse drug reactions (n = 7), followed by torasemide (n = 3). Adverse drug reactions associated with central nervous system were found to be the most frequent (42.8%) followed by musculo-skeletal complaints (23.8%) and gastro-intestinal disorders (14.3%).
conclusionsThe present pharmacovigilance study represents the adverse drug reaction profile of the antihypertensive medicines prescribed in our university teaching hospital. The above findings would be useful for physicians in rational prescribing. Calcium channel blockers were found to be the most frequently associated drugs with adverse drug reactions.
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