ArticleAmerican journal of surgery2013
Early-phase technetium-99m sestamibi scintigraphy can improve preoperative localization in primary hyperparathyroidism.
Article in American journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- A meta-analysis comparing the biochemistry of primary hyperparathyroidism in youths to the biochemistry of primary hyperparathyroidism in adults.The Journal of clinical endocrinology and metabolism · 2014Pooled it
- Transoral endoscopic parathyroidectomy vestibular approach: a novel scarless parathyroid surgery.Surgical endoscopy · 2017Trial
- A 20-year study on 190 patients with primary hyperparathyroidism in a developing country: Turkey experience.International surgery · 2015Article
- Parathyroid conditions in childhood.Seminars in pediatric surgery · 2014Review
- Radioguided parathyroidectomy effective in pediatric patients.The Journal of surgical research · 2013Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIn hyperparathyroidism, dual-phase technetium-99m sestamibi scintigraphy is important for parathyroid adenoma localization. We hypothesized that reviewing early-phase scans can increase localization in patients with primary hyperparathyroidism (PHPT).
methodsWe reviewed our prospectively maintained database for patients with sestamibi scans before parathyroidectomy for PHPT from 2001 to 2011. Early-phase scans were read and compared with the location of the gland(s) removed at operation.
resultsOf 902 patients identified, radiologists read 693 scans as positive. Of 209 negative scans, 141 (67%) were positive in the early phase; 135 (96%) correctly identified the side of the adenoma. Using radiologist reads, 35% of patients with negative scans and 41% of patients with falsely localized glands required bilateral exploration compared with 5% of patients with correctly localized glands.
conclusionsA review of early scans in patients with negative imaging increases accurate adenoma localization and allows for minimally invasive operations in more patients.
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Registered trials
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