ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2012
Treatment for sulfur mustard lung injuries; new therapeutic approaches from acute to chronic phase.
Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 50 citations in OpenAlex.
- Persistent neutrophilic inflammation is associated with delayed toxicity of phenylarsine oxide in lungs.Scientific reports · 2025Article
- Possible Treatment Approaches of Sulfur Mustard-Induced Lung Disorders, Experimental and Clinical Evidence, an Updated Review.Frontiers in medicine · 2022Review
- Long-term Health Outcomes Among Survivors Exposed to Sulfur Mustard in Iran.JAMA network open · 2020Article
- Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets.Annals of the New York Academy of Sciences · 2020Article
- Therapeutic options to treat mustard gas poisoning - Review.Caspian journal of internal medicine · 2019Review
- Sulfur mustard resistant keratinocytes obtained elevated glutathione levels and other changes in the antioxidative defense mechanism.Toxicology letters · 2018Article
- Effect of Melatonin Administration on Sleep Quality in Sulfur Mustard Exposed Patients with Sleep Disorders.Iranian journal of pharmaceutical research : IJPR · 2018Article
- The delayed effect of mustard gas on housekeeping gene expression in lung biopsy of chemical injuries.Biochemistry and biophysics reports · 2017Article
- From the Cover: Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
- Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.Pediatric pulmonology · 2015Article
- Characterization of Lung Fibroblasts More than Two Decades after Mustard Gas Exposure.PloS one · 2015Article
- Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.Toxicological sciences : an official journal of the Society of Toxicology · 2015Article
- Pirfenidone; can it be a new horizon for the treatment of pulmonary fibrosis in mustard gas-intoxicated patients?Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2013Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
objectiveSulfur mustard (SM) is one of the major potent chemical warfare and attractive weapons for terrorists. It has caused deaths to hundreds of thousands of victims in World War I and more recently during the Iran-Iraq war (1980-1988). It has ability to develop severe acute and chronic damage to the respiratory tract, eyes and skin. Understanding the acute and chronic biologic consequences of SM exposure may be quite essential for developing efficient prophylactic/therapeutic measures. One of the systems majorly affected by SM is the respiratory tract that numerous clinical studies have detailed processes of injury, diagnosis and treatments of lung. The low mortality rate has been contributed to high prevalence of victims and high lifetime morbidity burden. However, there are no curative modalities available in such patients. In this review, we collected and discussed the related articles on the preventive and therapeutic approaches to SM-induced respiratory injury and summarized what is currently known about the management and therapeutic strategies of acute and long-term consequences of SM lung injuries.
methodThis review was done by reviewing all papers found by searching following key words sulfur mustard; lung; chronic; acute; COPD; treatment.
resultsMustard lung has an ongoing pathological process and is active disorder even years after exposure to SM. Different drug classes have been studied, nevertheless there are no curative modalities for mustard lung.
conclusionComplementary studies on one hand regarding pharmacokinetic of drugs and molecular investigations are mandatory to obtain more effective treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.