Evidence map›Paper›PMID 23350745›Full record

ArticleMicrobial drug resistance (Larchmont, N.Y.)2013

Antimicrobial resistance genes in multidrug-resistant Salmonella enterica isolated from animals, retail meats, and humans in the United States and Canada.

LaShanda M Glenn, Rebecca L Lindsey, Jason P Folster, Gary Pecic, Patrick Boerlin, Mathew W Gilmour, Heather Harbottle, Shaohua Zhao, Patrick F McDermott, Paula J Fedorka-Cray and 1 more

Open access · greenAbstract read
In one paragraph

Article in Microbial drug resistance (Larchmont, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 66 citations in OpenAlex.

  1. Genetic Diversity inMicroorganisms · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Antibiotics (Basel, Switzerland) · 2021
    Article
  10. AttenuatedVaccines · 2020
    Article
  11. Article
  12. Population structure ofF1000Research · 2020
    Article
  13. Review
  14. Article
  15. Non-typhoidalPathogens (Basel, Switzerland) · 2019
    Review
  16. Article
  17. A review ofVeterinary world · 2019
    Review
  18. Article
  19. Article
  20. Antimicrobial usage and resistance in beef production.Journal of animal science and biotechnology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

LaShanda M GlennBacterial Epidemiology and Antimicrobial Resistance Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Richard B. Russell Research Center, Athens, GA 30605, USA.
Rebecca L Lindsey
Jason P Folster
Gary Pecic
Patrick Boerlin
Mathew W Gilmour
Heather Harbottle
Shaohua Zhao
Patrick F McDermott
Paula J Fedorka-Cray
Jonathan G Frye
Richard Wolf (Germany) · DECenters for Disease Control and Prevention · USUnited States Food and Drug Administration · USCenter for Veterinary Medicine · USOntario Veterinary CollegePublic Health Agency of Canada · CA

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Salmonella enterica is a prevalent foodborne pathogen that can carry multidrug resistance (MDR) and pose a threat to human health. Identifying the genetics associated with MDR in Salmonella isolated from animals, foods, and humans can help determine sources of MDR in food animals and their impact on humans. S. enterica serovars most frequently carrying MDR from healthy animals, retail meats, and human infections in the United States and Canada were identified and isolates resistant to the largest number of antimicrobials were chosen. Isolates were from U.S. slaughter (n=12), retail (9), and humans (9), and Canadian slaughter (9), retail (9), and humans (8; total n=56). These isolates were assayed by microarray for antimicrobial resistance and MDR plasmid genes. Genes detected encoded resistance to aminoglycosides (alleles of aac, aad, aph, strA/B); beta-lactams (bla(TEM), bla(CMY), bla(PSE-1)); chloramphenicol (cat, flo, cmlA); sulfamethoxazole (sulI); tetracycline (tet(A, B, C, D) and tetR); and trimethoprim (dfrA). Hybridization with IncA/C plasmid gene probes indicated that 27/56 isolates carried one of these plasmids; however, they differed in several variable regions. Cluster analysis based on genes detected separated most of the isolates into two groups, one with IncA/C plasmids and one without IncA/C plasmids. Other plasmid replicons were detected in all but one isolate, and included I1 (25/56), N (23/56), and FIB (10/56). The presence of different mobile elements along with similar resistance genes suggest that these genetic elements may acquire similar resistance cassettes, and serve as multiple sources for MDR in Salmonella from food animals, retail meats, and human infections.

Indexed as

AnimalsAnti-Bacterial AgentsCanadaCluster AnalysisDrug Resistance, Multiple, BacterialHumansMeatOligonucleotide Array Sequence AnalysisPlasmidsSalmonella entericaSalmonella InfectionsUnited StatesAnti-Bacterial Agents

Identifiers

PMID23350745
PMCPMC4665089
OpenAlexW2128519096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.