Evidence map›Paper›PMID 23350651›Full record

ArticleACS nano2013

Synthesis of long T₁ silicon nanoparticles for hyperpolarized ²⁹Si magnetic resonance imaging.

Tonya M Atkins, Maja C Cassidy, Menyoung Lee, Shreyashi Ganguly, Charles M Marcus, Susan M Kauzlarich

Abstract read
In one paragraph

Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. A Review on Metastable Silicon Allotropes.Materials (Basel, Switzerland) · 2021
    Review
  4. Article
  5. Synthesis of PEG-grafted boron doped Si nanocrystals.The Journal of chemical physics · 2019
    Article
  6. Article
  7. Article
  8. One-Pot Gram-Scale Synthesis of Hydrogen-Terminated Silicon Nanoparticles.Chemistry of materials : a publication of the American Chemical Society · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Targeted nanotechnology for cancer imaging.Advanced drug delivery reviews · 2014
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tonya M AtkinsDepartment of Chemistry, University of California, Davis, California 95616, USA.
Maja C Cassidy
Menyoung Lee
Shreyashi Ganguly
Charles M Marcus
Susan M Kauzlarich

Funding

Development of hyperpolarized silicon nanoparticles as molecular MRI agentsR21EB007486 · NIBIB · HARVARD UNIVERSITY · PI WALSWORTH, RONALD L · 2007 to 2008
$480k
NIBIB NIH HHS 1R21 EB007486-01A1NIBIB NIH HHS R21 EB007486
6 · The paper itself

Abstract

We describe the synthesis, materials characterization, and dynamic nuclear polarization (DNP) of amorphous and crystalline silicon nanoparticles for use as hyperpolarized magnetic resonance imaging (MRI) agents. The particles were synthesized by means of a metathesis reaction between sodium silicide (Na₄Si₄) and silicon tetrachloride (SiCl₄) and were surface functionalized with a variety of passivating ligands. The synthesis scheme results in particles of diameter ∼10 nm with long size-adjusted ²⁹Si spin-lattice relaxation (T₁) times (>600 s), which are retained after hyperpolarization by low-temperature DNP.

Indexed as

IsotopesMagnetic Resonance ImagingModels, MolecularMolecular ConformationNanoparticlesNanotechnologyParticle SizeSiliconTemperatureIsotopesSilicon

Identifiers

PMID23350651
PMCPMC3612549

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.