ArticlePloS one2013
Ectopic overexpression of SlHsfA3, a heat stress transcription factor from tomato, confers increased thermotolerance and salt hypersensitivity in germination in transgenic Arabidopsis.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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49 citing papers in PubMed, 120 citations in OpenAlex.
- Identification and functional characterization of heat shock transcription factor genes in Rhododendron Delavayi under heat stress.BMC plant biology · 2026Article
- Genome-Wide Analysis ofFood science & nutrition · 2026Article
- Review
- Evolutionary and functional insights into HSF gene family underpin thermal adaptation in the plateau plant Anisodus tanguticus.BMC plant biology · 2025Article
- Semi-automated high content analysis of pollen performance using tubetracker.Plant reproduction · 2025Article
- The CRY1-HsF predicted interaction interface serves as a molecular platform for bioengineering or selecting modulating mutants.Frontiers in plant science · 2025Article
- Genome-wide analysis of the HSF family in Allium sativum L. and AsHSFB1 overexpression in Arabidopsis under heat stress.BMC genomics · 2024Article
- MaHsf24, a novel negative modulator, regulates cold tolerance in banana fruits by repressing the expression of HSPs and antioxidant enzyme genes.Plant biotechnology journal · 2024Article
- Overexpression ofPlants (Basel, Switzerland) · 2024Article
- GDSL Lipase GeneAntioxidants (Basel, Switzerland) · 2024Article
- A Genome-Wide Analysis and Expression Profile of Heat Shock Transcription Factor (Hsf) Gene Family inPlants (Basel, Switzerland) · 2023Article
- Characterization of the Heat Shock Transcription Factor Family inInternational journal of molecular sciences · 2023Article
- Ectopic overexpression of TaHsfA5 promotes thermomorphogenesis in Arabidopsis thaliana and thermotolerance in Oryza sativa.Plant molecular biology · 2023Article
- Growth and Molecular Responses of Tomato to Prolonged and Short-Term Heat Exposure.International journal of molecular sciences · 2023Article
- Heat Shock Transcription Factor GhHSFB2a Is Crucial for Cotton Resistance toInternational journal of molecular sciences · 2023Article
- Various tomato cultivars display contrasting morphological and molecular responses to a chronic heat stress.Frontiers in plant science · 2023Article
- Genome-wide analysis of the heat shock transcription factor family reveals saline-alkali stress responses inPeerJ · 2023Article
- Functional characterization of two WD40 family proteins, Alr0671 and All2352, from Anabaena PCC 7120 and deciphering their role in abiotic stress management.Plant molecular biology · 2022Article
- Analyzing the regulatory role of heat shock transcription factors in plant heat stress tolerance: a brief appraisal.Molecular biology reports · 2022Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant heat stress transcription factors (Hsfs) are the critical components involved in mediating responses to various environmental stressors. However, the detailed roles of many plant Hsfs are far from fully understood. In this study, an Hsf (SlHsfA3) was isolated from the cultivated tomato (Solanum lycopersicum, Sl) and functionally characterized at the genetic and developmental levels. The nucleus-localized SlHsfA3 was basally and ubiquitously expressed in different plant organs. The expression of SlHsfA3 was induced dramatically by heat stress, moderately by high salinity, and slightly by drought, but was not induced by abscisic acid (ABA). The ectopic overexpression of SlHsfA3 conferred increased thermotolerance and late flowering phenotype to transgenic Arabidopsis plants. Moreover, SlHsfA3 played a negative role in controlling seed germination under salt stress. RNA-sequencing data demonstrated that a number of heat shock proteins (Hsps) and stress-associated genes were induced in Arabidopsis plants overexpressing SlHsfA3. A gel shift experiment and transient expression assays in Nicotiana benthamiana leaves demonstrated that SlHsfA3 directly activates the expression of SlHsp26.1-P and SlHsp21.5-ER. Taken together, our results suggest that SlHsfA3 behaves as a typical Hsf to contribute to plant thermotolerance. The late flowering and seed germination phenotypes and the RNA-seq data derived from SlHsfA3 overexpression lines lend more credence to the hypothesis that plant Hsfs participate in diverse physiological and biochemical processes related to adverse conditions.
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