ArticlePloS one2013
Risk factors for severe cholera among children under five in rural and urban Bangladesh, 2000-2008: a hospital-based surveillance study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Individual and Household Risk Factors for Symptomatic Cholera Infection: A Systematic Review and Meta-analysis.The Journal of infectious diseases · 2018Pooled it
- Ranked Placement of Phage Predation as a Determinant of Dehydration Severity Among Cholera Patients in Bangladesh.The Journal of infectious diseases · 2026Article
- Estimating the Transmission Potential of Symptomatic and Asymptomatic Cholera Cases From Household Microbiological and Clinical Data.The Journal of infectious diseases · 2026Article
- Estimating the Transmission Potential of Symptomatic and Asymptomatic Cholera Cases from Household Microbiological and Clinical Data.medRxiv : the preprint server for health sciences · 2026Article
- Article
- A protracted cholera outbreak in Nairobi City County accentuated by mass gathering events, Kenya, 2017.PloS one · 2024Article
- Article
- National Hospital-Based Sentinel Surveillance for Cholera in Bangladesh: Epidemiological Results from 2014 to 2021.The American journal of tropical medicine and hygiene · 2023Article
- Oral cholera vaccine coverage evaluation survey: Forcibly Displaced Myanmar Nationals and host community in Cox's Bazar, Bangladesh.Frontiers in public health · 2023Article
- Factors associated with diarrheal disease among children aged 1-5 years in a cholera epidemic in rural Haiti.PLoS neglected tropical diseases · 2021Article
- Spatiotemporal Patterns of Cholera Hospitalization in Vellore, India.International journal of environmental research and public health · 2019Article
- Cholera Control and Prevention in Bangladesh: An Evaluation of the Situation and Solutions.The Journal of infectious diseases · 2018Article
- Upstream watershed condition predicts rural children's health across 35 developing countries.Nature communications · 2017Article
- Natural Disasters and Cholera Outbreaks: Current Understanding and Future Outlook.Current environmental health reports · 2017Review
- Assessing the risk factors of cholera epidemic in the Buea Health District of Cameroon.BMC public health · 2015Article
- Risk factors for diarrhea hospitalization in Bangladesh, 2000-2008: a case-case study of cholera and shigellosis.BMC infectious diseases · 2014Article
- Importance of cholera and other etiologies of acute diarrhea in post-earthquake Port-au-Prince, Haiti.The American journal of tropical medicine and hygiene · 2014Article
- Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundChildren under five bear the largest cholera burden. We therefore sought to identify modifiable risk factors among Bangladeshi children. METHODOLOGY/PRINCIPAL
findingsWe used multivariate Poisson regression to assess risk factors for severe cholera among diarrheal patients presenting at hospitals in Matlab (rural) and Dhaka (urban), Bangladesh. Risk increased with age. Compared to those under one, rural and urban four-year-olds had adjusted risk ratios (aRR) of 4.17 (95% confidence interval (CI) 2.43-7.15) and 6.32 (95% CI: 4.63-8.63), respectively. Breastfeeding halved the risk in both rural (aRR = 0.49, 95% CI: 0.35-0.67) and urban (aRR = 0.51, 95% CI: 0.41-0.62) settings. Rural children's risk decreased with maternal education (P-trend: <0.001) and increased among those with a family member with diarrhea in the past week (aRR = 1.61, 95% CI: 1.22-2.14) and those with prior vitamin A supplementation (aRR = 1.65, 95% CI: 1.12-2.43). Urban children whose mothers daily (aRR = 0.41, 95% CI: 0.21-0.79) or occasionally (aRR = 0.55, 95% CI: 0.36-0.84) read a newspaper experienced reduced risk. Urban children from households with incomes between 34-84 USD/month had a 30% increased risk compared to those from households with incomes >84 USD/month. CONCLUSION/SIGNIFICANCE: Increasing age, lower socioeconomic status, and lack of breastfeeding are key correlates of increased risk for cholera hospitalization among those under five in rural and urban Bangladesh. In addition, having a family member with diarrhea in the past week was associated with increased risk among rural children. Continued attention should be directed to the promotion of breastfeeding. Further research is needed to elucidate the relationship between maternal education and cholera risk. Renewed research regarding the use of chemoprophylaxis among family members of cholera cases may be warranted in rural endemic settings.
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