ArticlePloS one2013
Identification of novel protein-protein interactions of Yersinia pestis type III secretion system by yeast two hybrid system.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Class II chaperones: indispensable components of the Gram-negative bacterial T3SS as guardians of translocators.Archives of microbiology · 2026Review
- Functional analysis of ascP in Aeromonas veronii TH0426 reveals a key role in the regulation of virulence.Journal of microbiology (Seoul, Korea) · 2022Article
- Subversion of GBP-mediated host defense by E3 ligases acquired during Yersinia pestis evolution.Nature communications · 2022Article
- Use of magnetic nanotrap particles in capturing Yersinia pestis virulence factors, nucleic acids and bacteria.Journal of nanobiotechnology · 2021Article
- Protein Acetylation Mediated by YfiQ and CobB Is Involved in the Virulence and Stress Response of Yersinia pestis.Infection and immunity · 2018Article
- An Interaction between the Inner Rod Protein YscI and the Needle Protein YscF Is Required to Assemble the Needle Structure of theThe Journal of biological chemistry · 2017Article
- Computational approach to predict species-specific type III secretion system (T3SS) effectors using single and multiple genomes.BMC genomics · 2016Article
- Structure and biophysics of type III secretion in bacteria.Biochemistry · 2013Review
- Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis.PloS one · 2013Article
- Yersinia pestis detection by loop-mediated isothermal amplification combined with magnetic bead capture of DNA.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type III secretion system (T3SS) of the plague bacterium Y. pestis encodes a syringe-like structure consisting of more than 20 proteins, which can inject virulence effectors into host cells to modulate the cellular functions. Here in this report, interactions among the possible components in T3SS of Yersinia pestis were identified using yeast mating technique. A total of 57 genes, including all the pCD1-encoded genes except those involved in plasmid replication and partition, pseudogenes, and the putative transposase genes, were subjected to yeast mating analysis. 21 pairs of interaction proteins were identified, among which 9 pairs had been previously reported and 12 novel pairs were identified in this study. Six of them were tested by GST pull down assay, and interaction pairs of YscG-SycD, YscG-TyeA, YscI-YscF, and YopN-YpCD1.09c were successfully validated, suggesting that these interactions might play potential roles in function of Yersinia T3SS. Several potential new interactions among T3SS components could help to understand the assembly and regulation of Yersinia T3SS.
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