Evidence map›Paper›PMID 23349116›Full record

ArticleJournal of biomedical materials research. Part A2013

Recyclable synthesis, characterization, and antimicrobial activity of chitosan-based polysaccharide composite materials.

Chieu D Tran, Simon Duri, April L Harkins

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. [Advance of new dressings for promoting skin wound healing].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019
    Review
  6. Review
  7. Article
  8. Article
  9. Cellulose, chitosan, and keratin composite materials. Controlled drug release.Langmuir : the ACS journal of surfaces and colloids · 2015
    Article
  10. Article
  11. Article
  12. Enantiomeric selective adsorption of amino acid by polysaccharide composite materials.Langmuir : the ACS journal of surfaces and colloids · 2014
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chieu D TranDepartment of Chemistry, Marquette University, Milwaukee, Wisconsin 53201, USA. chieu.tran@marquette.edu
Simon Duri
April L Harkins
Marquette University · US

Funding

Polysaccharide Ecocomposite Materials: Recyclable Synthesis and ApplicationsR15GM099033 · NIGMS · MARQUETTE UNIVERSITY · PI TRAN, CHIEU D. · 2012 to 2012
$339k
NIGMS NIH HHS R15 GM099033NIGMS NIH HHS R15GM099033
6 · The paper itself

Abstract

We have successfully developed a simple and totally recyclable method to synthesize novel, biocompatible, and biodegradable composite materials from cellulose (CEL) and chitosan (CS). In this method, [BMIm(+) Cl(-) ], an ionic liquid (IL), was used as a green solvent to dissolve and synthesize the [CEL+CS] composites. Since, the IL can be removed from the composites by washing them with water, and recovered by distilling the washed solution, the method is totally recyclable. Spectroscopic and imaging techniques including XRD, FTIR, NIR, and SEM were used to monitor the dissolution, to characterize and to confirm that CEL and CS were successfully regenerated. More importantly, we have successfully demonstrated that [CEL+CS] composite is particularly suited for many applications including antimicrobial property. This is because the composites have combined advantages of their components, namely superior chemical and mechanical stability (from CEL) and bactericide (from CS). Results of tensile strength measurements clearly indicate that adding CEL into CS substantially increase its tensile strength. Up to 5× increase in tensile strength can be achieved by adding 80% of CEL into CS. Results of in vitro antibacterial assays confirm that CS retains its antibacterial property in the composite. More importantly, the composites reported here can inhibit growth of wider range of bacteria than other CS-based materials prepared by conventional methods; that is over 24 h period, the composites substantially inhibited growth of bacteria such as MRSA, VRE, S. aureus, E. coli. These are bacteria that are often found to have the highest morbidity and mortality associated with wound infections.

Indexed as

Anti-Bacterial AgentsBacteriaBacterial InfectionsBiocompatible MaterialsCelluloseChitosanGreen Chemistry TechnologyHumansAnti-Bacterial AgentsBiocompatible MaterialsCelluloseChitosan

Identifiers

PMID23349116
PMCPMC3638083
OpenAlexW2166668279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.