ArticleMicrobiologyOpen2013
Microbiota diversity and stability of the preterm neonatal ileum and colon of two infants.
Article in MicrobiologyOpen, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03590418 (Intestinal Microbial Diversity of Small Bowel Stoma Effluent and Colonic Feces of Children With Short Bowel Syndrome), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intestinal Microbial Diversity of Small Bowel Stoma Effluent and Colonic Feces of Children With Short Bowel Syndrome
Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Delving the depths of 'terra incognita' in the human intestine - the small intestinal microbiota.Nature reviews. Gastroenterology & hepatology · 2025Review
- Changes in Microbiota Profile in the Proximal Remnant Intestine in Infants Undergoing Surgery Requiring Enterostomy.Microorganisms · 2023Article
- Human milk microbial species are associated with infant head-circumference during early and late lactation in Guatemalan mother-infant dyads.Frontiers in microbiology · 2022Article
- Nutritional Factors Associated with Late-Onset Sepsis in Very Low Birth Weight Newborns.Nutrients · 2021Article
- Article
- Inflammation in Mental Disorders: Is the Microbiota the Missing Link?Neuroscience bulletin · 2020Review
- The complex microbiome from native semen to embryo culture environment in human in vitro fertilization procedure.Reproductive biology and endocrinology : RB&E · 2020Article
- Article
- The Impact of Oral Sodium Chloride Supplementation on Thrive and the Intestinal Microbiome in Neonates With Small Bowel Ostomies: A Prospective Cohort Study.Frontiers in immunology · 2020Article
- Colonisation of the proximal intestinal remnant in newborn infants with enterostomy: a longitudinal study protocol.BMJ open · 2019Observational
- Microbiome and Mental Health, Specifically as It Relates to Adolescents.Current psychiatry reports · 2019Review
- Spatial and Temporal Analysis of the Stomach and Small-Intestinal Microbiota in Fasted Healthy Humans.mSphere · 2019Article
- A Metagenomics Study on Hirschsprung's Disease Associated Enterocolitis: Biodiversity and Gut Microbial Homeostasis Depend on Resection Length and Patient's Clinical History.Frontiers in pediatrics · 2019Article
- Effects of synbiotics on ileal microbiota.The Indian journal of medical research · 2018Article
- Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration.The Journal of physiology · 2017Review
- Longitudinal Survey of Microbiota in Hospitalized Preterm Very-Low-Birth-Weight Infants.Journal of pediatric gastroenterology and nutrition · 2016Article
- Article
- Potential use of multi-strain synbiotics for improving postnatal head circumference.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The composition of the microbiota associated with the human ileum and colon in the early weeks of life of two preterm infants was examined, with particular emphasis on the Lactobacillus and Bifidobacterium members. Culturing work showed that bifidobacteria and lactobacilli in the ileostomy changed over time, compared with the colostomy effluent where there was far less variation. The colostomy infant was dominated by two phyla, Actinobacteria and Firmicutes, while in the ileostomy samples, Proteobacteria emerged at the expense of Actinobacteria. Bacteroidetes were only detected following the reversal of the ileostomy in the final fecal sample and were not detected in any colonic fluid samples. Clostridia levels were unstable in the colostomy fluid, suggesting that the ileostomy/colostomy itself influenced the gut microbiota, in particular the strict anaerobes. Pyrosequencing analysis of microbiota composition indicated that bifidobacteria and lactobacilli are among the dominant genera in both the ileal and colonic fluids. Bifidobacteria and lactobacilli levels were unstable in the ileostomy fluid, with large reductions in numbers and relative proportions of both observed. These decreases were characterized by an increase in proportions of Streptococcus and Enterobacteriaceae. Clostridium was detected only in the colonic effluent, with large changes in the relative proportions over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.