Evidence map›Paper›PMID 23349015›Full record

ArticleCarcinogenesis2013

Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation.

Xiaolin Hu, Mary A Zimmerman, Kankana Bardhan, Dafeng Yang, Jennifer L Waller, Georgia B Liles, Jeffrey R Lee, Raphael Pollock, Dina Lev, Carl F Ware and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Carcinogenesis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Lymphotoxin-driven cancer cell eradication by tumoricidal CD8bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Regulatory T cell and endothelial cell crosstalk.Nature reviews. Immunology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Impact of p53 on Aristolochic Acid I-Induced Gene Expression In Vivo.International journal of molecular sciences · 2019
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Xiaolin HuDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
Mary A Zimmerman
Kankana Bardhan
Dafeng Yang
Jennifer L Waller
Georgia B Liles
Jeffrey R Lee
Raphael Pollock
Dina Lev
Carl F Ware
Ellen Garber
Veronique Bailly
Jeffrey L Browning
Kebin Liu
Augusta University Health · USBiogen (United States) · USAugusta University · USBiogen (Switzerland) · CHCancer Research And Biostatistics · USDiscovery Institute · USSarcoma Oncology Center · USSociety of Surgical Oncology · US

Funding

HVEM-BTLA system in InflammationR01AI067890 · NIAID · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI WARE, CARL F · 2007 to 2016
$4.3M
Role of IRF8 in Tumor Rejection and SuppressionR01CA133085 · NCI · AUGUSTA UNIVERSITY · PI LIU, KEBIN · 2008 to 2019
$2.9M
NCI NIH HHS CA133085
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisCaspasesCell Line, TumorColonic NeoplasmsHumansLigandsLymphotoxin beta ReceptorMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMitochondriaNF-kappa BTransplantation, HeterologousTumor Suppressor ProteinsCaspasesLigandsLymphotoxin beta ReceptorNF-kappa BTumor Suppressor Proteins

Identifiers

PMID23349015
PMCPMC3643415
OpenAlexW2128410785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.