Evidence map›Paper›PMID 23348523›Full record

ReviewSeminars in cell & developmental biology2013

Peptide regulators of peripheral taste function.

Cedrick D Dotson, Maartje C P Geraedts, Steven D Munger

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. Review
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  11. Do Gut Microbes Taste?Nutrients · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Cedrick D DotsonDepartment of Neuroscience, University of Florida College of Medicine, McKnight Brain Institute, Gainesville, FL 32611, USA.
Maartje C P Geraedts
Steven D Munger
University of Maryland, Baltimore · USFlorida College · US

Funding

Mechanisms of alimentary chemosensationR01DC010110 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI MUNGER, STEVEN D · 2009 to 2013
$1.5M
Core Center: NIDCD Research Core Center P30P30DC010364 · NIDCD · UNIVERSITY OF FLORIDA · PI ACHE, BARRY W. · 2009 to 2012
$1.3M
NIDCD NIH HHS DC010110NIDCD NIH HHS DC010364NIDCD NIH HHS P30 DC010364NIDCD NIH HHS R01 DC010110
6 · The paper itself

Abstract

The peripheral sensory organ of the gustatory system, the taste bud, contains a heterogeneous collection of sensory cells. These taste cells can differ in the stimuli to which they respond and the receptors and other signaling molecules they employ to transduce and encode those stimuli. This molecular diversity extends to the expression of a varied repertoire of bioactive peptides that appear to play important functional roles in signaling taste information between the taste cells and afferent sensory nerves and/or in processing sensory signals within the taste bud itself. Here, we review studies that examine the expression of bioactive peptides in the taste bud and the impact of those peptides on taste functions. Many of these peptides produced in taste buds are known to affect appetite, satiety or metabolism through their actions in the brain, pancreas and other organs, suggesting a functional link between the gustatory system and the neural and endocrine systems that regulate feeding and nutrient utilization.

Indexed as

TasteAnimalsHumansPeptidesSignal TransductionTaste BudsPeptides

Identifiers

PMID23348523
PMCPMC3612364
OpenAlexW2090703501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.