Evidence map›Paper›PMID 23347916›Full record

ArticleHearing research2013

Rapid measurement of auditory filter shape in mice using the auditory brainstem response and notched noise.

Ioan A Lina, Amanda M Lauer

Open access · greenAbstract read
In one paragraph

Article in Hearing research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Engineering olivocochlear inhibition to reduce acoustic trauma.Molecular therapy. Methods & clinical development · 2023
    Article
  2. Acoustic Trauma Increases Ribbon Number and Size in Outer Hair Cells of the Mouse Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2021
    Article
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  14. The role of harmonic resolvability in pitch perception in a vocal nonhuman primate, the common marmoset (Callithrix jacchus).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ioan A LinaJohns Hopkins University School of Medicine, Department of Otolaryngology - HNS, Center for Hearing and Balance, 515 Traylor, 720 Rutland Ave., Baltimore, MD 21205, United States.
Amanda M Lauer
Johns Hopkins Medicine · US

Funding

The Histology CoreP30DC005211 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI FUCHS, PAUL ALBERT · 2002 to 2016
$9.1M
Training Program in Hearing and BalanceT32DC000023 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CULLEN, KATHLEEN E · 1989 to 2025
$8.7M
Medial olivocochlear protection from environmental noise exposureF32DC009353 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI LAUER, AMANDA M. · 2008 to 2009
$101k
NIDCD NIH HHS F32 DC009353NIDCD NIH HHS P30 DC005211NIDCD NIH HHS T32 DC000023
6 · The paper itself

Abstract

The notched noise method is an effective procedure for measuring frequency resolution and auditory filter shapes in both human and animal models of hearing. Briefly, auditory filter shape and bandwidth estimates are derived from masked thresholds for tones presented in noise containing widening spectral notches. As the spectral notch widens, increasingly less of the noise falls within the auditory filter and the tone becomes more detectible until the notch width exceeds the filter bandwidth. Behavioral procedures have been used for the derivation of notched noise auditory filter shapes in mice; however, the time and effort needed to train and test animals on these tasks renders a constraint on the widespread application of this testing method. As an alternative procedure, we combined relatively non-invasive auditory brainstem response (ABR) measurements and the notched noise method to estimate auditory filters in normal-hearing mice at center frequencies of 8, 11.2, and 16 kHz. A complete set of simultaneous masked thresholds for a particular tone frequency were obtained in about an hour. ABR-derived filter bandwidths broadened with increasing frequency, consistent with previous studies. The ABR notched noise procedure provides a fast alternative to estimating frequency selectivity in mice that is well-suited to high through-put or time-sensitive screening.

Indexed as

Auditory PerceptionPerceptual MaskingAcoustic StimulationAnimalsAudiometry, Pure-ToneAuditory ThresholdBrain StemElectroencephalographyEvoked Potentials, Auditory, Brain StemMiceMice, Inbred CBANoisePitch PerceptionTime Factors

Identifiers

PMID23347916
PMCPMC3639490
OpenAlexW2021755025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.