ArticleJournal of the American Chemical Society2013
Nonlinear scaling of surface water diffusion with bulk water viscosity of crowded solutions.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
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- Spin-labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells.Applied magnetic resonance · 2024Article
- Nanoscale water-polymer interactions tune macroscopic diffusivity of water in aqueous poly(ethylene oxide) solutions.Chemical science · 2024Article
- Dynamic computed tomography manifestations of simulated wooden foreign bodies in blood-saline mixtures with variable concentrations and retention times.Scientific reports · 2023Article
- Tau Aggregation Propensity Engrained in Its Solution State.The journal of physical chemistry. B · 2015Article
- Optimization and prediction of the electron-nuclear dipolar and scalar interaction inChemical science · 2015Article
- Anomalously Rapid Hydration Water Diffusion Dynamics Near DNA Surfaces.Journal of the American Chemical Society · 2015Article
- Cholesterol enhances surface water diffusion of phospholipid bilayers.The Journal of chemical physics · 2014Article
- Liquid but durable: molecular dynamics simulations explain the unique properties of archaeal-like membranes.Scientific reports · 2014Article
- Probing membrane protein structure using water polarization transfer solid-state NMR.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2014Article
- Probing water density and dynamics in the chaperonin GroEL cavity.Journal of the American Chemical Society · 2014Article
- Specific ions modulate diffusion dynamics of hydration water on lipid membrane surfaces.Journal of the American Chemical Society · 2014Article
- Crowding induced collective hydration of biological macromolecules over extended distances.Journal of the American Chemical Society · 2014Article
- Quantitative cw Overhauser effect dynamic nuclear polarization for the analysis of local water dynamics.Progress in nuclear magnetic resonance spectroscopy · 2013Review
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3 authors.
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Abstract
The translational hydration dynamics within 0.5-1.5 nm of the surface of a DPPC liposome, a model biomacromolecular surface, is analyzed by the recently developed Overhauser dynamic nuclear polarization (ODNP) technique. We find that dramatic changes to the bulk solvent cause only weak changes in the surface hydration dynamics. Specifically, both a >10-fold increase in bulk viscosity and the restriction of diffusion by confinement on a multiple nm length-scale change the local translational diffusion coefficient of the surface water surrounding the lipid bilayer by <2.5-fold. By contrast, previous ODNP studies have shown that changes to the biomacromolecular surface induced by folding, binding, or aggregation can cause local hydration dynamics to vary by factors of up to 30. We suggest that the surface topology and chemistry at the ≤1.5 nm scale, rather than the characteristics of the solvent, nearly exclusively determine the macromolecule's surface hydration dynamics.
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