ArticleInternational neurourology journal2012
Association of insulin resistance with overactive bladder in female patients.
Article in International neurourology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Machine Learning Model Based on Insulin Resistance Metagenes Underpins Genetic Basis of Type 2 Diabetes.Biomolecules · 2023Pooled it
- Metabolic syndrome, inflammation and lower urinary tract symptoms: possible translational links.Prostate cancer and prostatic diseases · 2016Pooled it
- Associations Between Risk Factors and Overactive Bladder: A Meta-analysis.Female pelvic medicine & reconstructive surgeryPooled it
- Preclinical animal models of lower urinary tract dysfunction associated with metabolic syndrome.Nature reviews. Urology · 2026Review
- Myostatin-dependent detrusor remodelling mediates contractility impairment in diabetic rats' bladder - a maximal elastance analysis.The Journal of physiology · 2026Article
- Association between hepatitis C virus and overactive bladder: a cross-sectional study based on the 2013-2018 NHANES.BMC urology · 2026Article
- Associations of estimated glucose disposal rate and overactive bladder and the potential mediating role of systemic inflammation: NHANES 2005-2018.Diabetology & metabolic syndrome · 2026Article
- Impact of Adjunctive Myo-Inositol and Magnesium Therapy on Paediatric Overactive Bladder: A Retrospective Analysis.Children (Basel, Switzerland) · 2026Article
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- METS-VF outperforms traditional adiposity indices in predicting overactive bladder risk: a NHANES-based cross-sectional study.Translational andrology and urology · 2026Article
- Depression mediates the association between lipid accumulation products and overactive bladder.Scientific reports · 2025Article
- Association between cardiometabolic index and overactive bladder in adult American women: A cross-sectional study.PloS one · 2025Article
- Association of neutrophil to high-density lipoprotein cholesterol ratio with overactive bladder: a population-based study.Frontiers in endocrinology · 2025Article
- Association between triglyceride glucose body mass index and urinary incontinence: a cross-sectional study from the National Health and Nutrition Examination Survey (NHANES) 2001 to 2018.Lipids in health and disease · 2024Article
- Correlation Between Insulin Resistance and Urinary Incontinence in Female Patients with Type 2 Diabetes Mellitus.International urogynecology journal · 2024Article
- The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go?International neurourology journal · 2024Article
- Intake of dietary flavonoids in relation to overactive bladder among U.S. adults: a nutritional strategy for improving urinary health.Frontiers in nutrition · 2024Article
- Association between weight-adjusted waist index and overactive bladder: a cross-sectional study based on 2009-2018 NHANES.Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMetabolic syndrome and obesity have been advocated to be risk factors for the development of overactive bladder (OAB). Additionally, insulin resistance is the underlying mechanism of metabolic syndrome. We aimed to investigate the association of insulin resistance with overactive bladder in female patients.
methodsWe prospectively conducted the study in our urology department. Female patients aged between 30 and 76 years old applied to our policlinics with or without OAB symptoms were enrolled. One hundred and twenty-two patients with OAB and 62 age-matched controls without OAB were included into the study. Fasting serum insulin, glucose, high-density lipoprotein (HDL-c), and triglycerides levels were measured. Insulin resistance value was obtained via the homeostasis model assessment of insulin resistance (HOMA-IR) calculator. The chi-square and Mann-Whitney U tests were used to compare differences in variables.
resultsSerum insulin level was found higher in female patients with OAB (11.5±6.2 µU/mL) relative to controls (6.4±2.1 µU/mL), statistically significant (P=0.036). In addition, HOMA-IR was significantly found higher in the OAB group, 2.86 (0.76 to 17.04) in comparison to controls, 1.32 (0.67 to 224), P=0.018. High-density lipoprotein cholesterol levels (HDL-c) were significantly found lower in females with OAB.
conclusionsInsulin resistance can be associated to overactive bladder and may play significant role in pathogenesis.
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Registered trials
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