ArticleISRN cardiology2013
Pathobiology of obstructive sleep apnea-related dyslipidemia: focus on the liver.
Article in ISRN cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Beneficial effect of continuous positive airway pressure on lipid profiles in obstructive sleep apnea: a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2015Pooled it
- Correlation of Dyslipidemia and Inflammation With Obstructive Sleep Apnea Severity.Frontiers in pharmacology · 2022Article
- The Relationship Between Obstructive Sleep Apnea and Ruptured Intracranial Aneurysms.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Effect of CPAP therapy on liver disease in patients with OSA: a review.Sleep & breathing = Schlaf & Atmung · 2018Review
- Systems Biology Genetic Approach Identifies Serotonin Pathway as a Possible Target for Obstructive Sleep Apnea: Results from a Literature Search Review.Sleep disorders · 2017Article
- Role of sleep quality in the metabolic syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2016Review
- Impact of Continuous Positive Airway Pressure on Cardiovascular Risk Factors in High-Risk Patients.Current atherosclerosis reports · 2015Review
- Clinical manifestations of sleep apnea.Journal of thoracic disease · 2015Review
- Nonalcoholic fatty pancreatic disease and cardio-metabolic risk: is there is a place for obstructive sleep apnea?Cardiovascular diabetology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea and dyslipidemia are common medical disorders that independently increase vascular morbidity and mortality. Current animal and human data show that, indeed, obstructive sleep apnea may mediate pathological alterations in cholesterol and triglyceride metabolism. The mechanisms involved are increased lipolysis, decreased lipoprotein clearance, and enhanced lipid output from the liver. Human evidence shows that the treatment of obstructive sleep apnea with continuous positive airway pressure leads to an improvement of postprandial hyperlipidemia. However, more studies are needed, to clarify the pathophysiology of the interrelationship between obstructive sleep apnea and dyslipidemia and whether treatment of obstructive sleep apnea will lead to an improvement in the lipid profile and, more importantly, reduce hyperlipidemia-related vascular outcomes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.