Evidence map›Paper›PMID 23346349›Full record

ArticleScientific reports2013

Sedimentation of macroscopic rigid knots and its relation to gel electrophoretic mobility of DNA knots.

Cédric Weber, Mathias Carlen, Giovanni Dietler, Eric J Rawdon, Andrzej Stasiak

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. DNA-Topology Simplification by Topoisomerases.Molecules (Basel, Switzerland) · 2021
    Review
  3. Article
  4. Article
  5. Topological patterns in two-dimensional gel electrophoresis of DNA knots.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Cédric WeberKing's College London, Materials and Molecular Modelling, The Strand, London, UK.
Mathias Carlen
Giovanni Dietler
Eric J Rawdon
Andrzej Stasiak
École Polytechnique Fédérale de Lausanne · CHKing's College London · GBUniversity of Lausanne · CHUniversity of St. Thomas - Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We address the general question of the extent to which the hydrodynamic behaviour of microscopic freely fluctuating objects can be reproduced by macrosopic rigid objects. In particular, we compare the sedimentation speeds of knotted DNA molecules undergoing gel electrophoresis to the sedimentation speeds of rigid stereolithographic models of ideal knots in both water and silicon oil. We find that the sedimentation speeds grow roughly linearly with the average crossing number of the ideal knot configurations, and that the correlation is stronger within classes of knots. This is consistent with previous observations with DNA knots in gel electrophoresis.

Indexed as

Nucleic Acid ConformationDNA, CircularElectrophoresisGelsSiliconWaterDNA, CircularGelsSiliconWater

Identifiers

PMID23346349
PMCPMC3549607
OpenAlexW1973787087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.