Evidence map›Paper›PMID 23346151›Full record

ArticleHepatitis monthly2012

High Serum Levels of TGF-β in Iranians With Chronic HBV Infection.

Hossein Khorramdelazad, Gholamhossein Hassanshahi, Behzad Nasiri Ahmadabadi, Mohammad Kazemi Arababadi

Abstract read
In one paragraph

Article in Hepatitis monthly, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Hepatitis B envelope antigen increases Tregs by converting CD4+CD25Experimental and therapeutic medicine · 2020
    Article
  4. The Binary Classification Of Chronic Diseases.Journal of inflammation research · 2019
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hossein KhorramdelazadMolecular Medicine Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, IR Iran.
Gholamhossein Hassanshahi
Behzad Nasiri Ahmadabadi
Mohammad Kazemi Arababadi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transforming growth factor-β (TGF-β) is an important cytokine with anti-inflammatory properties.

objectivesThe main purpose of this study was to compare the serum levels of TGF-β in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran. PATIENTS AND

methodsSixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-β in both groups.

resultsOur results revealed that the serum levels of TGF-β were significantly increased in CHB patients in compare to healthy controls.

conclusionsAccording to this result, it may be concluded that high serum levels of TGF-β may be a mechanism by which immune response against HBV is suppressed.

Indexed as

Hepatitis B, ChronicTransforming Growth Factor Beta

Identifiers

PMID23346151
PMCPMC3549612

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.